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Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy.
Heidegger S, Stritzke F, Dahl S, Daßler-Plenker J, Joachim L, Buschmann D, Fan K, Sauer CM, Ludwig N, Winter C, Enssle S, Li S, Perl M, Görgens A, Haas T, Orberg ET, Göttert S, Wölfel C, Engleitner T, Cortés-Ciriano I, Rad R, Herr W, Giebel B, Ruland J, Bassermann F, Coch C, Hartmann G, Poeck H. Heidegger S, et al. Cell Rep Med. 2023 Sep 19;4(9):101171. doi: 10.1016/j.xcrm.2023.101171. Epub 2023 Aug 31. Cell Rep Med. 2023. PMID: 37657445 Free PMC article.
Genomic basis for RNA alterations in cancer.
PCAWG Transcriptome Core Group; Calabrese C, Davidson NR, Demircioğlu D, Fonseca NA, He Y, Kahles A, Lehmann KV, Liu F, Shiraishi Y, Soulette CM, Urban L, Greger L, Li S, Liu D, Perry MD, Xiang Q, Zhang F, Zhang J, Bailey P, Erkek S, Hoadley KA, Hou Y, Huska MR, Kilpinen H, Korbel JO, Marin MG, Markowski J, Nandi T, Pan-Hammarström Q, Pedamallu CS, Siebert R, Stark SG, Su H, Tan P, Waszak SM, Yung C, Zhu S, Awadalla P, Creighton CJ, Meyerson M, Ouellette BFF, Wu K, Yang H; PCAWG Transcriptome Working Group; Brazma A, Brooks AN, Göke J, Rätsch G, Schwarz RF, Stegle O, Zhang Z; PCAWG Consortium. PCAWG Transcriptome Core Group, et al. Nature. 2020 Feb;578(7793):129-136. doi: 10.1038/s41586-020-1970-0. Epub 2020 Feb 5. Nature. 2020. PMID: 32025019 Free PMC article.
Specialized replication mechanisms maintain genome stability at human centromeres.
Scelfo A, Angrisani A, Grillo M, Barnes BM, Muyas F, Sauer CM, Leung CWB, Dumont M, Grison M, Mazaud D, Garnier M, Guintini L, Nelson L, Esashi F, Cortés-Ciriano I, Taylor SS, Déjardin J, Wilhelm T, Fachinetti D. Scelfo A, et al. Among authors: cortes ciriano i. Mol Cell. 2024 Mar 21;84(6):1003-1020.e10. doi: 10.1016/j.molcel.2024.01.018. Epub 2024 Feb 14. Mol Cell. 2024. PMID: 38359824
Predicting response to immune checkpoint blockade therapy among mismatch repair-deficient patients using mutational signatures.
Gulhan DC, Viswanadham V, Muyas F, Jin H, Foote MB, Lee JJ, Barras D, Jung YL, Ljungstrom V, Rousseau B, Galor A, Diplas BH, Maron SB, Cleary JM, Cortés-Ciriano I, Park PJ. Gulhan DC, et al. Among authors: cortes ciriano i. medRxiv [Preprint]. 2024 Jan 21:2024.01.19.24301236. doi: 10.1101/2024.01.19.24301236. medRxiv. 2024. PMID: 38293061 Free PMC article. Preprint.
A comprehensive clinically informed map of dependencies in cancer cells and framework for target prioritization.
Pacini C, Duncan E, Gonçalves E, Gilbert J, Bhosle S, Horswell S, Karakoc E, Lightfoot H, Curry E, Muyas F, Bouaboula M, Pedamallu CS, Cortes-Ciriano I, Behan FM, Zalmas LP, Barthorpe A, Francies H, Rowley S, Pollard J, Beltrao P, Parts L, Iorio F, Garnett MJ. Pacini C, et al. Among authors: cortes ciriano i. Cancer Cell. 2024 Feb 12;42(2):301-316.e9. doi: 10.1016/j.ccell.2023.12.016. Epub 2024 Jan 11. Cancer Cell. 2024. PMID: 38215750 Free article.
Transcriptional signals of transformation in human cancer.
Kildisiute G, Kalyva M, Elmentaite R, van Dongen S, Thevanesan C, Piapi A, Ambridge K, Prigmore E, Haniffa M, Teichmann SA, Straathof K, Cortés-Ciriano I, Behjati S, Young MD. Kildisiute G, et al. Among authors: cortes ciriano i. Genome Med. 2024 Jan 9;16(1):8. doi: 10.1186/s13073-023-01279-z. Genome Med. 2024. PMID: 38195504 Free PMC article.
Genomic data resources of the Brain Somatic Mosaicism Network for neuropsychiatric diseases.
Garrison MA, Jang Y, Bae T, Cherskov A, Emery SB, Fasching L, Jones A, Moldovan JB, Molitor C, Pochareddy S, Peters MA, Shin JH, Wang Y, Yang X, Akbarian S, Chess A, Gage FH, Gleeson JG, Kidd JM, McConnell M, Mills RE, Moran JV, Park PJ, Sestan N, Urban AE, Vaccarino FM, Walsh CA, Weinberger DR, Wheelan SJ, Abyzov A; BSMN Consortium. Garrison MA, et al. Sci Data. 2023 Nov 20;10(1):813. doi: 10.1038/s41597-023-02645-7. Sci Data. 2023. PMID: 37985666 Free PMC article.
117 results