Cortés R - Search Results

1

The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia.

Erdem A, Marin S, Pereira-Martins DA, Cortés R, Cunningham A, Pruis MG, de Boer B, van den Heuvel FAJ, Geugien M, Wierenga ATJ, Brouwers-Vos AZ, Rego EM, Huls G, Cascante M, Schuringa JJ. Erdem A, et al. Among authors: cortes r. Nat Commun. 2022 Mar 1;13(1):1105. doi: 10.1038/s41467-022-28737-3. Nat Commun. 2022. PMID: 35232995 Free PMC article.

2

Novel celastrol derivatives with improved selectivity and enhanced antitumour activity: Design, synthesis and biological evaluation.

Figueiredo SAC, Salvador JAR, Cortés R, Cascante M. Figueiredo SAC, et al. Among authors: cortes r. Eur J Med Chem. 2017 Sep 29;138:422-437. doi: 10.1016/j.ejmech.2017.06.029. Epub 2017 Jun 16. Eur J Med Chem. 2017. PMID: 28688281

3

Design, synthesis and biological evaluation of novel C-29 carbamate celastrol derivatives as potent and selective cytotoxic compounds.

Figueiredo SAC, Salvador JAR, Cortés R, Cascante M. Figueiredo SAC, et al. Among authors: cortes r. Eur J Med Chem. 2017 Oct 20;139:836-848. doi: 10.1016/j.ejmech.2017.08.058. Epub 2017 Aug 26. Eur J Med Chem. 2017. PMID: 28865279

4

Oxidative Pentose Phosphate Pathway Enzyme 6-Phosphogluconate Dehydrogenase Plays a Key Role in Breast Cancer Metabolism.

Polat IH, Tarrado-Castellarnau M, Bharat R, Perarnau J, Benito A, Cortés R, Sabatier P, Cascante M. Polat IH, et al. Among authors: cortes r. Biology (Basel). 2021 Jan 23;10(2):85. doi: 10.3390/biology10020085. Biology (Basel). 2021. PMID: 33498665 Free PMC article.

5

Quantitative proteomic approach to understand metabolic adaptation in non-small cell lung cancer.

Martín-Bernabé A, Cortés R, Lehmann SG, Seve M, Cascante M, Bourgoin-Voillard S. Martín-Bernabé A, et al. Among authors: cortes r. J Proteome Res. 2014 Nov 7;13(11):4695-704. doi: 10.1021/pr500327v. Epub 2014 Aug 25. J Proteome Res. 2014. PMID: 25029028

6

New betulinic acid derivatives induce potent and selective antiproliferative activity through cell cycle arrest at the S phase and caspase dependent apoptosis in human cancer cells.

Santos RC, Salvador JA, Cortés R, Pachón G, Marín S, Cascante M. Santos RC, et al. Among authors: cortes r. Biochimie. 2011 Jun;93(6):1065-75. doi: 10.1016/j.biochi.2011.02.014. Epub 2011 Mar 4. Biochimie. 2011. PMID: 21377507

7

Seven-membered cycloplatinated complexes as a new family of anticancer agents. X-ray characterization and preliminary biological studies.

Cortés R, Crespo M, Davin L, Martín R, Quirante J, Ruiz D, Messeguer R, Calvis C, Baldomà L, Badia J, Font-Bardía M, Calvet T, Cascante M. Cortés R, et al. Eur J Med Chem. 2012 Aug;54:557-66. doi: 10.1016/j.ejmech.2012.06.002. Epub 2012 Jun 12. Eur J Med Chem. 2012. PMID: 22770537

8

A novel cyclometallated Pt(II)-ferrocene complex induces nuclear FOXO3a localization and apoptosis and synergizes with cisplatin to inhibit lung cancer cell proliferation.

Cortés R, Tarrado-Castellarnau M, Talancón D, López C, Link W, Ruiz D, Centelles JJ, Quirante J, Cascante M. Cortés R, et al. Metallomics. 2014 Mar;6(3):622-33. doi: 10.1039/c3mt00194f. Epub 2014 Feb 3. Metallomics. 2014. PMID: 24492855

9

Quantitative Proteomic Approach Reveals Altered Metabolic Pathways in Response to the Inhibition of Lysine Deacetylases in A549 Cells under Normoxia and Hypoxia.

Martín-Bernabé A, Tarragó-Celada J, Cunin V, Michelland S, Cortés R, Poignant J, Boyault C, Rachidi W, Bourgoin-Voillard S, Cascante M, Seve M. Martín-Bernabé A, et al. Among authors: cortes r. Int J Mol Sci. 2021 Mar 25;22(7):3378. doi: 10.3390/ijms22073378. Int J Mol Sci. 2021. PMID: 33806075 Free PMC article.

10

Pt(II) complexes with (N,N') or (C,N,E)(-) (E=N,S) ligands: cytotoxic studies, effect on DNA tertiary structure and structure-activity relationships.

Albert J, Bosque R, Crespo M, Granell J, López C, Cortés R, Gonzalez A, Quirante J, Calvis C, Messeguer R, Baldomà L, Badia J, Cascante M. Albert J, et al. Among authors: cortes r. Bioorg Med Chem. 2013 Jul 15;21(14):4210-7. doi: 10.1016/j.bmc.2013.05.005. Epub 2013 May 14. Bioorg Med Chem. 2013. PMID: 23735827

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