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Calcium-sensing receptor antagonists abrogate airway hyperresponsiveness and inflammation in allergic asthma.
Yarova PL, Stewart AL, Sathish V, Britt RD Jr, Thompson MA, P Lowe AP, Freeman M, Aravamudan B, Kita H, Brennan SC, Schepelmann M, Davies T, Yung S, Cholisoh Z, Kidd EJ, Ford WR, Broadley KJ, Rietdorf K, Chang W, Bin Khayat ME, Ward DT, Corrigan CJ, T Ward JP, Kemp PJ, Pabelick CM, Prakash YS, Riccardi D. Yarova PL, et al. Among authors: corrigan cj. Sci Transl Med. 2015 Apr 22;7(284):284ra60. doi: 10.1126/scitranslmed.aaa0282. Epub 2015 Apr 22. Sci Transl Med. 2015. PMID: 25904744 Free PMC article.
Asthma. Eosinophils and neutrophils.
Kay AB, Corrigan CJ. Kay AB, et al. Among authors: corrigan cj. Br Med Bull. 1992 Jan;48(1):51-64. doi: 10.1093/oxfordjournals.bmb.a072541. Br Med Bull. 1992. PMID: 1617394 Review.
Characterization of Negative Allosteric Modulators of the Calcium-Sensing Receptor for Repurposing as a Treatment of Asthma.
Yarova PL, Huang P, Schepelmann MW, Bruce R, Ecker R, Nica R, Telezhkin V, Traini D, Gomes Dos Reis L, Kidd EJ, Ford WR, Broadley KJ, Kariuki BM, Corrigan CJ, Ward JPT, Kemp PJ, Riccardi D. Yarova PL, et al. Among authors: corrigan cj. J Pharmacol Exp Ther. 2021 Jan;376(1):51-63. doi: 10.1124/jpet.120.000281. Epub 2020 Oct 28. J Pharmacol Exp Ther. 2021. PMID: 33115824
Systemic glucocorticoid reduces bronchial mucosal activation of activator protein 1 components in glucocorticoid-sensitive but not glucocorticoid-resistant asthmatic patients.
Loke TK, Mallett KH, Ratoff J, O'Connor BJ, Ying S, Meng Q, Soh C, Lee TH, Corrigan CJ. Loke TK, et al. Among authors: corrigan cj. J Allergy Clin Immunol. 2006 Aug;118(2):368-75. doi: 10.1016/j.jaci.2006.04.055. Epub 2006 Jun 27. J Allergy Clin Immunol. 2006. PMID: 16890760 Clinical Trial.
Diminished sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma.
Mahn K, Hirst SJ, Ying S, Holt MR, Lavender P, Ojo OO, Siew L, Simcock DE, McVicker CG, Kanabar V, Snetkov VA, O'Connor BJ, Karner C, Cousins DJ, Macedo P, Chung KF, Corrigan CJ, Ward JP, Lee TH. Mahn K, et al. Among authors: corrigan cj. Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10775-80. doi: 10.1073/pnas.0902295106. Epub 2009 Jun 16. Proc Natl Acad Sci U S A. 2009. PMID: 19541629 Free PMC article.
232 results