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Four evolutionary trajectories underlie genetic intratumoral variation in childhood cancer.
Karlsson J, Valind A, Holmquist Mengelbier L, Bredin S, Cornmark L, Jansson C, Wali A, Staaf J, Viklund B, Øra I, Börjesson A, Backman T, Braekeveldt N, Sandstedt B, Pal N, Isaksson A, Lackner BG, Jonson T, Bexell D, Gisselsson D. Karlsson J, et al. Among authors: cornmark l. Nat Genet. 2018 Jul;50(7):944-950. doi: 10.1038/s41588-018-0131-y. Epub 2018 Jun 4. Nat Genet. 2018. PMID: 29867221
Loss of NF2 defines a genetic subgroup of non-FOS-rearranged osteoblastoma.
Saba KH, Cornmark L, Hofvander J, Magnusson L, Nilsson J, van den Bos H, Spierings DC, Foijer F, Staaf J, Brosjö O, Sumathi VP, Lam SW, Szuhai K, Bovée JV, Kovac M, Baumhoer D, Styring E, Nord KH. Saba KH, et al. Among authors: cornmark l. J Pathol Clin Res. 2020 Oct;6(4):231-237. doi: 10.1002/cjp2.172. Epub 2020 Jun 16. J Pathol Clin Res. 2020. PMID: 32542935 Free PMC article.
Disruption of the TP53 locus in osteosarcoma leads to TP53 promoter gene fusions and restoration of parts of the TP53 signalling pathway.
Saba KH, Difilippo V, Kovac M, Cornmark L, Magnusson L, Nilsson J, van den Bos H, Spierings DC, Bidgoli M, Jonson T, Sumathi VP, Brosjö O, Staaf J, Foijer F, Styring E, Nathrath M, Baumhoer D, Nord KH. Saba KH, et al. Among authors: cornmark l. J Pathol. 2024 Feb;262(2):147-160. doi: 10.1002/path.6219. Epub 2023 Nov 27. J Pathol. 2024. PMID: 38010733
PKCalpha expression is a marker for breast cancer aggressiveness.
Lønne GK, Cornmark L, Zahirovic IO, Landberg G, Jirström K, Larsson C. Lønne GK, et al. Among authors: cornmark l. Mol Cancer. 2010 Apr 14;9:76. doi: 10.1186/1476-4598-9-76. Mol Cancer. 2010. PMID: 20398285 Free PMC article.
New light on Smac mimetics and breast cancer.
Cornmark L, Larsson C. Cornmark L, et al. Cell Death Dis. 2016 Apr 7;7(4):e2178. doi: 10.1038/cddis.2016.81. Cell Death Dis. 2016. PMID: 27054333 Free PMC article. No abstract available.
Genetic profiling of a chondroblastoma-like osteosarcoma/malignant phosphaturic mesenchymal tumor of bone reveals a homozygous deletion of CDKN2A, intragenic deletion of DMD, and a targetable FN1-FGFR1 gene fusion.
Saba KH, Cornmark L, Rissler M, Fioretos T, Åström K, Haglund F, Rosenberg AE, Brosjö O, Nord KH. Saba KH, et al. Among authors: cornmark l. Genes Chromosomes Cancer. 2019 Oct;58(10):731-736. doi: 10.1002/gcc.22764. Epub 2019 May 15. Genes Chromosomes Cancer. 2019. PMID: 31066955
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