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Enhancer profiling identifies epigenetic markers of endocrine resistance and reveals therapeutic options for metastatic castration-resistant prostate cancer patients.
Severson TM, Zhu Y, Prekovic S, Schuurman K, Nguyen HM, Brown LG, Hakkola S, Kim Y, Kneppers J, Linder S, Stelloo S, Lieftink C, van der Heijden M, Nykter M, van der Noort V, Sanders J, Morris B, Jenster G, van Leenders GJ, Pomerantz M, Freedman ML, Beijersbergen RL, Urbanucci A, Wessels L, Corey E, Zwart W, Bergman AM. Severson TM, et al. Among authors: corey e. medRxiv [Preprint]. 2023 Feb 24:2023.02.24.23286403. doi: 10.1101/2023.02.24.23286403. medRxiv. 2023. PMID: 36865297 Free PMC article. Preprint.
A genome-wide CRISPR screen in human prostate cancer cells reveals drivers of macrophage-mediated cell killing and positions AR as a tumor-intrinsic immunomodulator.
Zaalberg A, Minnee E, Mayayo-Peralta I, Schuurman K, Gregoricchio S, van Schaik TA, Hoekman L, Li D, Corey E, Janssen H, Lieftink C, Prekovic S, Altelaar M, Nelson PS, Beijersbergen RL, Zwart W, Bergman A. Zaalberg A, et al. Among authors: corey e. bioRxiv [Preprint]. 2023 Jun 7:2023.06.06.543873. doi: 10.1101/2023.06.06.543873. bioRxiv. 2023. PMID: 37333335 Free PMC article. Preprint.
Increased chromatin accessibility drives transition to androgen receptor splice variant dependence in castration-resistant prostate cancer.
Poluben L, Nouri M, Liang J, Varkaris A, Ersoy-Fazlioglu B, Voznesensky O, Lee II, Qiu X, Cato L, Seo JH, Freedman ML, Sowalsky AG, Lack NA, Corey E, Nelson PS, Brown M, Long HW, Balk SP, Russo JW. Poluben L, et al. Among authors: corey e. bioRxiv [Preprint]. 2024 Jan 12:2024.01.10.575110. doi: 10.1101/2024.01.10.575110. bioRxiv. 2024. PMID: 38260576 Free PMC article. Preprint.
BET inhibitors as a therapeutic intervention in gastrointestinal gene signature-positive castration-resistant prostate cancer.
Shukla S, Li D, Nguyen H, Conner J, Bayshtok G, Cho WH, Pachai M, Teri N, Campeau E, Attwell S, Trojer P, Ostrovnaya I, Gopalan A, Corey E, Chi P, Chen Y. Shukla S, et al. Among authors: corey e. bioRxiv [Preprint]. 2024 Mar 13:2024.03.09.584256. doi: 10.1101/2024.03.09.584256. bioRxiv. 2024. PMID: 38559135 Free PMC article. Preprint.
GD2 and its biosynthetic enzyme GD3 synthase promote tumorigenesis in prostate cancer by regulating cancer stem cell behavior.
Bhat AM, Mohapatra BC, Luan H, Mushtaq I, Chakraborty S, Kumar S, Wu W, Nolan B, Dutta S, Stock MD, Schott M, Meza JL, Lele SM, Lin MF, Cook LM, Corey E, Morrissey C, Coulter DW, Rowley J, Natarajan A, Datta K, Band V, Band H. Bhat AM, et al. Among authors: corey e. bioRxiv [Preprint]. 2024 Apr 22:2023.03.18.533299. doi: 10.1101/2023.03.18.533299. bioRxiv. 2024. PMID: 36993422 Free PMC article. Preprint.
LSD1 inhibition suppresses ASCL1 and de-represses YAP1 to drive potent activity against neuroendocrine prostate cancer.
Mandl A, Jasmine S, Krueger T, Kumar R, Coleman IM, Dalrymple SL, Antony L, Rosen DM, Jing Y, Hanratty B, Patel RA, Jin-Yih L, Dias J, Celatka CA, Tapper AE, Kleppe M, Kanayama M, Speranzini V, Wang YZ, Luo J, Corey E, Sena LA, Casero RA, Lotan T, Trock BJ, Kachhap SK, Denmeade SR, Carducci MA, Mattevi A, Haffner MC, Nelson PS, Rienhoff HY, Isaacs JT, Brennen WN. Mandl A, et al. Among authors: corey e. bioRxiv [Preprint]. 2024 Jan 22:2024.01.17.576106. doi: 10.1101/2024.01.17.576106. bioRxiv. 2024. PMID: 38328141 Free PMC article. Preprint.
Assessment of TROP2, CEACAM5 and DLL3 in metastatic prostate cancer: Expression landscape and molecular correlates.
Ajkunic A, Sayar E, Roudier MP, Patel RA, Coleman IM, De Sarkar N, Hanratty B, Adil M, Zhao J, Zaidi S, True LD, Sperger JM, Cheng HH, Yu EY, Montgomery RB, Hawley JE, Ha G, Persse T, Galipeau P, Lee JK, Harmon SA, Corey E, Lang JM, Sawyers CL, Morrissey C, Schweizer MT, Gulati R, Nelson PS, Haffner MC. Ajkunic A, et al. Among authors: corey e. NPJ Precis Oncol. 2024 May 17;8(1):104. doi: 10.1038/s41698-024-00599-6. NPJ Precis Oncol. 2024. PMID: 38760413 Free PMC article.
640 results