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T-cell Acute Lymphoblastic Leukemia: A Roadmap to Targeted Therapies.
Cordo' V, van der Zwet JCG, Canté-Barrett K, Pieters R, Meijerink JPP. Cordo' V, et al. Blood Cancer Discov. 2020 Nov 24;2(1):19-31. doi: 10.1158/2643-3230.BCD-20-0093. eCollection 2021 Jan. Blood Cancer Discov. 2020. PMID: 34661151 Free PMC article. Review.
[No title available]
[No authors listed] [No authors listed] PMID: 35015662
MEF2C opposes Notch in lymphoid lineage decision and drives leukemia in the thymus.
Canté-Barrett K, Meijer MT, Cordo' V, Hagelaar R, Yang W, Yu J, Smits WK, Nulle ME, Jansen JP, Pieters R, Yang JJ, Haigh JJ, Goossens S, Meijerink JP. Canté-Barrett K, et al. Among authors: cordo v. JCI Insight. 2022 Jul 8;7(13):e150363. doi: 10.1172/jci.insight.150363. JCI Insight. 2022. PMID: 35536646 Free PMC article.
STAT5 does not drive steroid resistance in T-cell acute lymphoblastic leukemia despite the activation of BCL2 and BCLXL following glucocorticoid treatment.
Van der Zwet JCG, Cordo' V, Buijs-Gladdines JGCAM, Hagelaar R, Smits WK, Vroegindeweij E, Graus LTM, Poort V, Nulle M, Pieters R, Meijerink JPP. Van der Zwet JCG, et al. Among authors: cordo v. Haematologica. 2023 Mar 1;108(3):732-746. doi: 10.3324/haematol.2021.280405. Haematologica. 2023. PMID: 35734930 Free PMC article.
MAPK-ERK is a central pathway in T-cell acute lymphoblastic leukemia that drives steroid resistance.
van der Zwet JCG, Buijs-Gladdines JGCAM, Cordo' V, Debets DO, Smits WK, Chen Z, Dylus J, Zaman GJR, Altelaar M, Oshima K, Bornhauser B, Bourquin JP, Cools J, Ferrando AA, Vormoor J, Pieters R, Vormoor B, Meijerink JPP. van der Zwet JCG, et al. Among authors: cordo v. Leukemia. 2021 Dec;35(12):3394-3405. doi: 10.1038/s41375-021-01291-5. Epub 2021 May 18. Leukemia. 2021. PMID: 34007050 Free article.
GATA3-Controlled Nucleosome Eviction Drives MYC Enhancer Activity in T-cell Development and Leukemia.
Belver L, Yang AY, Albero R, Herranz D, Brundu FG, Quinn SA, Pérez-Durán P, Álvarez S, Gianni F, Rashkovan M, Gurung D, Rocha PP, Raviram R, Reglero C, Cortés JR, Cooke AJ, Wendorff AA, Cordó V, Meijerink JP, Rabadan R, Ferrando AA. Belver L, et al. Cancer Discov. 2019 Dec;9(12):1774-1791. doi: 10.1158/2159-8290.CD-19-0471. Epub 2019 Sep 13. Cancer Discov. 2019. PMID: 31519704 Free PMC article.
PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma.
Bleu M, Gaulis S, Lopes R, Sprouffske K, Apfel V, Holwerda S, Pregnolato M, Yildiz U, Cordoʹ V, Dost AFM, Knehr J, Carbone W, Lohmann F, Lin CY, Bradner JE, Kauffmann A, Tordella L, Roma G, Galli GG. Bleu M, et al. Nat Commun. 2019 Aug 20;10(1):3739. doi: 10.1038/s41467-019-11672-1. Nat Commun. 2019. PMID: 31431624 Free PMC article.
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