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Integrated molecular signaling involving mitochondrial dysfunction and alteration of cell metabolism induced by tyrosine kinase inhibitors in cancer.
Rodríguez-Hernández MA, de la Cruz-Ojeda P, López-Grueso MJ, Navarro-Villarán E, Requejo-Aguilar R, Castejón-Vega B, Negrete M, Gallego P, Vega-Ochoa Á, Victor VM, Cordero MD, Del Campo JA, Bárcena JA, Padilla CA, Muntané J. Rodríguez-Hernández MA, et al. Among authors: cordero md. Redox Biol. 2020 Sep;36:101510. doi: 10.1016/j.redox.2020.101510. Epub 2020 May 23. Redox Biol. 2020. PMID: 32593127 Free PMC article. Review.
Amitriptyline induces mitophagy that precedes apoptosis in human HepG2 cells.
Villanueva-Paz M, Cordero MD, Pavón AD, Vega BC, Cotán D, De la Mata M, Oropesa-Ávila M, Alcocer-Gomez E, de Lavera I, Garrido-Maraver J, Carrascosa J, Zaderenko AP, Muntané J, de Miguel M, Sánchez-Alcázar JA. Villanueva-Paz M, et al. Among authors: cordero md. Genes Cancer. 2016 Jul;7(7-8):260-277. doi: 10.18632/genesandcancer.114. Genes Cancer. 2016. PMID: 27738496 Free PMC article.
Two coffins and a funeral: early or late caspase activation determines two types of apoptosis induced by DNA damaging agents.
Oropesa-Ávila M, de la Cruz-Ojeda P, Porcuna J, Villanueva-Paz M, Fernández-Vega A, de la Mata M, de Lavera I, Rivero JM, Luzón-Hidalgo R, Álvarez-Córdoba M, Cotán D, Zaderenko AP, Cordero MD, Sánchez-Alcázar JA. Oropesa-Ávila M, et al. Among authors: cordero md. Apoptosis. 2017 Mar;22(3):421-436. doi: 10.1007/s10495-016-1337-z. Apoptosis. 2017. PMID: 27943067
Stress-Induced NLRP3 Inflammasome in Human Diseases.
Alcocer-Gómez E, Castejón-Vega B, Cordero MD. Alcocer-Gómez E, et al. Among authors: cordero md. Adv Protein Chem Struct Biol. 2017;108:127-162. doi: 10.1016/bs.apcsb.2017.02.002. Epub 2017 Mar 27. Adv Protein Chem Struct Biol. 2017. PMID: 28427559 Review.
NLRP3-inflammasome inhibition prevents high fat and high sugar diets-induced heart damage through autophagy induction.
Pavillard LE, Cañadas-Lozano D, Alcocer-Gómez E, Marín-Aguilar F, Pereira S, Robertson AAB, Muntané J, Ryffel B, Cooper MA, Quiles JL, Bullón P, Ruiz-Cabello J, Cordero MD. Pavillard LE, et al. Among authors: cordero md. Oncotarget. 2017 Sep 8;8(59):99740-99756. doi: 10.18632/oncotarget.20763. eCollection 2017 Nov 21. Oncotarget. 2017. PMID: 29245937 Free PMC article.
Autophagic dysfunction in patients with Papillon-Lefèvre syndrome is restored by recombinant cathepsin C treatment.
Bullón P, Castejón-Vega B, Román-Malo L, Jimenez-Guerrero MP, Cotán D, Forbes-Hernandez TY, Varela-López A, Pérez-Pulido AJ, Giampieri F, Quiles JL, Battino M, Sánchez-Alcázar JA, Cordero MD. Bullón P, et al. Among authors: cordero md. J Allergy Clin Immunol. 2018 Oct;142(4):1131-1143.e7. doi: 10.1016/j.jaci.2018.01.018. Epub 2018 Feb 2. J Allergy Clin Immunol. 2018. PMID: 29410039
Inflammasomes in Clinical Practice: A Brief Introduction.
Alcocer-Gómez E, Castejón-Vega B, López-Sánchez M, Cordero MD. Alcocer-Gómez E, et al. Among authors: cordero md. Exp Suppl. 2018;108:1-8. doi: 10.1007/978-3-319-89390-7_1. Exp Suppl. 2018. PMID: 30536165
NLRP3 Inflammasome Inhibition by MCC950 in Aged Mice Improves Health via Enhanced Autophagy and PPARα Activity.
Marín-Aguilar F, Castejón-Vega B, Alcocer-Gómez E, Lendines-Cordero D, Cooper MA, de la Cruz P, Andújar-Pulido E, Pérez-Alegre M, Muntané J, Pérez-Pulido AJ, Ryffel B, Robertson AAB, Ruiz-Cabello J, Bullón P, Cordero MD. Marín-Aguilar F, et al. Among authors: cordero md. J Gerontol A Biol Sci Med Sci. 2020 Jul 13;75(8):1457-1464. doi: 10.1093/gerona/glz239. J Gerontol A Biol Sci Med Sci. 2020. PMID: 31603987
NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice.
Marín-Aguilar F, Lechuga-Vieco AV, Alcocer-Gómez E, Castejón-Vega B, Lucas J, Garrido C, Peralta-Garcia A, Pérez-Pulido AJ, Varela-López A, Quiles JL, Ryffel B, Flores I, Bullón P, Ruiz-Cabello J, Cordero MD. Marín-Aguilar F, et al. Among authors: cordero md. Aging Cell. 2020 Jan;19(1):e13050. doi: 10.1111/acel.13050. Epub 2019 Oct 18. Aging Cell. 2020. PMID: 31625260 Free PMC article.
Blockade of the NLRP3 inflammasome improves metabolic health and lifespan in obese mice.
Cañadas-Lozano D, Marín-Aguilar F, Castejón-Vega B, Ryffel B, Navarro-Pando JM, Ruiz-Cabello J, Alcocer-Gómez E, Bullón P, Cordero MD. Cañadas-Lozano D, et al. Among authors: cordero md. Geroscience. 2020 Apr;42(2):715-725. doi: 10.1007/s11357-019-00151-6. Epub 2020 Jan 23. Geroscience. 2020. PMID: 31975052 Free PMC article.
114 results