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HMGA1 chromatin regulators induce transcriptional networks involved in GATA2 and proliferation during MPN progression.
Li L, Kim JH, Lu W, Williams DM, Kim J, Cope L, Rampal RK, Koche RP, Xian L, Luo LZ, Vasiljevic M, Matson DR, Zhao ZJ, Rogers O, Stubbs MC, Reddy K, Romero AR, Psaila B, Spivak JL, Moliterno AR, Resar LMS. Li L, et al. Among authors: cope l. Blood. 2022 May 5;139(18):2797-2815. doi: 10.1182/blood.2021013925. Blood. 2022. PMID: 35286385 Free PMC article.
The High Mobility Group A1 (HMGA1) gene is highly overexpressed in human uterine serous carcinomas and carcinosarcomas and drives Matrix Metalloproteinase-2 (MMP-2) in a subset of tumors.
Hillion J, Roy S, Heydarian M, Cope L, Xian L, Koo M, Luo LZ, Kellyn K, Ronnett BM, Huso T, Armstrong D, Reddy K, Huso DL, Resar LMS. Hillion J, et al. Among authors: cope l. Gynecol Oncol. 2016 Jun;141(3):580-587. doi: 10.1016/j.ygyno.2016.03.020. Epub 2016 Apr 8. Gynecol Oncol. 2016. PMID: 27001612 Free PMC article.
High mobility group A1 (HMGA1) protein and gene expression correlate with ER-negativity and poor outcomes in breast cancer.
Gorbounov M, Carleton NM, Asch-Kendrick RJ, Xian L, Rooper L, Chia L, Cimino-Mathews A, Cope L, Meeker A, Stearns V, Veltri RW, Bae YK, Resar LMS. Gorbounov M, et al. Among authors: cope l. Breast Cancer Res Treat. 2020 Jan;179(1):25-35. doi: 10.1007/s10549-019-05419-1. Epub 2019 Sep 17. Breast Cancer Res Treat. 2020. PMID: 31531802 Free PMC article.
368 results