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Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven.
Attard G, Reid AH, Yap TA, Raynaud F, Dowsett M, Settatree S, Barrett M, Parker C, Martins V, Folkerd E, Clark J, Cooper CS, Kaye SB, Dearnaley D, Lee G, de Bono JS. Attard G, et al. Among authors: cooper cs. J Clin Oncol. 2008 Oct 1;26(28):4563-71. doi: 10.1200/JCO.2007.15.9749. Epub 2008 Jul 21. J Clin Oncol. 2008. PMID: 18645193 Clinical Trial.
Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer.
Jhavar S, Brewer D, Edwards S, Kote-Jarai Z, Attard G, Clark J, Flohr P, Christmas T, Thompson A, Parker M, Shepherd C, Stenman UH, Marchbank T, Playford RJ, Woodhouse C, Ogden C, Fisher C, Kovacs G, Corbishley C, Jameson C, Norman A, De-Bono J, Bjartell A, Eeles R, Cooper CS. Jhavar S, et al. Among authors: cooper cs. BJU Int. 2009 May;103(9):1256-69. doi: 10.1111/j.1464-410X.2008.08200.x. Epub 2008 Nov 25. BJU Int. 2009. PMID: 19040532
ETS gene fusions in prostate cancer.
Clark JP, Cooper CS. Clark JP, et al. Among authors: cooper cs. Nat Rev Urol. 2009 Aug;6(8):429-39. doi: 10.1038/nrurol.2009.127. Nat Rev Urol. 2009. PMID: 19657377 Review.
A census of amplified and overexpressed human cancer genes.
Santarius T, Shipley J, Brewer D, Stratton MR, Cooper CS. Santarius T, et al. Among authors: cooper cs. Nat Rev Cancer. 2010 Jan;10(1):59-64. doi: 10.1038/nrc2771. Nat Rev Cancer. 2010. PMID: 20029424 Review.
Expression of Bcl-2, p53, and MDM2 in localized prostate cancer with respect to the outcome of radical radiotherapy dose escalation.
Vergis R, Corbishley CM, Thomas K, Horwich A, Huddart R, Khoo V, Eeles R, Sydes MR, Cooper CS, Dearnaley D, Parker C. Vergis R, et al. Among authors: cooper cs. Int J Radiat Oncol Biol Phys. 2010 Sep 1;78(1):35-41. doi: 10.1016/j.ijrobp.2009.07.1728. Epub 2010 Jan 21. Int J Radiat Oncol Biol Phys. 2010. PMID: 20092961 Clinical Trial.
Prognostic value of blood mRNA expression signatures in castration-resistant prostate cancer: a prospective, two-stage study.
Olmos D, Brewer D, Clark J, Danila DC, Parker C, Attard G, Fleisher M, Reid AH, Castro E, Sandhu SK, Barwell L, Oommen NB, Carreira S, Drake CG, Jones R, Cooper CS, Scher HI, de Bono JS. Olmos D, et al. Among authors: cooper cs. Lancet Oncol. 2012 Nov;13(11):1114-24. doi: 10.1016/S1470-2045(12)70372-8. Epub 2012 Oct 9. Lancet Oncol. 2012. PMID: 23059046 Free PMC article.
439 results