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β-cell function is regulated by metabolic and epigenetic programming of islet-associated macrophages, involving Axl, Mertk, and TGFβ receptor signaling.
Thai LM, O'Reilly L, Reibe-Pal S, Sue N, Holliday H, Small L, Schmitz-Peiffer C, Dhenni R, Wang-Wei Tsai V, Norris N, Yau B, Zhang X, Lee K, Yan C, Shi YC, Kebede MA, Brink R, Cooney GJ, Irvine KM, Breit SN, Phan TG, Swarbrick A, Biden TJ. Thai LM, et al. Among authors: cooney gj. iScience. 2023 Mar 22;26(4):106477. doi: 10.1016/j.isci.2023.106477. eCollection 2023 Apr 21. iScience. 2023. PMID: 37091234 Free PMC article.
Erratum: Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet.
Yau B, Naghiloo S, Diaz-Vegas A, Carr AV, Van Gerwen J, Needham EJ, Jevon D, Chen SY, Hoehn KL, Brandon AE, Macia L, Cooney GJ, Shortreed MR, Smith LM, Keller MP, Thorn P, Larance M, James DE, Humphrey SJ, Kebede MA. Yau B, et al. Among authors: cooney gj. iScience. 2023 Dec 14;27(1):108707. doi: 10.1016/j.isci.2023.108707. eCollection 2024 Jan 19. iScience. 2023. PMID: 38188515 Free PMC article.
Hepatic lipid droplet-associated proteome changes distinguish dietary-induced fatty liver from glucose tolerance in male mice.
Van Woerkom A, Harney DJ, Nagarajan SR, Hakeem-Sanni MF, Lin J, Hooke M, Pilpitel T, Cooney GJ, Larance M, Saunders DN, Brandon AE, Hoy AJ. Van Woerkom A, et al. Among authors: cooney gj. Am J Physiol Endocrinol Metab. 2024 Apr 24. doi: 10.1152/ajpendo.00013.2024. Online ahead of print. Am J Physiol Endocrinol Metab. 2024. PMID: 38656127
Insulin sensitivity is preserved in mice made obese by feeding a high starch diet.
Brandon AE, Small L, Nguyen TV, Suryana E, Gong H, Yassmin C, Hancock SE, Pulpitel T, Stonehouse S, Prescott L, Kebede MA, Yau B, Quek LE, Kowalski GM, Bruce CR, Turner N, Cooney GJ. Brandon AE, et al. Among authors: cooney gj. Elife. 2022 Nov 17;11:e79250. doi: 10.7554/eLife.79250. Elife. 2022. PMID: 36394259 Free PMC article.
Systems-level analysis of insulin action in mouse strains provides insight into tissue- and pathway-specific interactions that drive insulin resistance.
Nelson ME, Madsen S, Cooke KC, Fritzen AM, Thorius IH, Masson SWC, Carroll L, Weiss FC, Seldin MM, Potter M, Hocking SL, Fazakerley DJ, Brandon AE, Thillainadesan S, Senior AM, Cooney GJ, Stöckli J, James DE. Nelson ME, et al. Among authors: cooney gj. Cell Metab. 2022 Feb 1;34(2):227-239.e6. doi: 10.1016/j.cmet.2021.12.013. Epub 2022 Jan 11. Cell Metab. 2022. PMID: 35021042 Free article.
Nutritional reprogramming of mouse liver proteome is dampened by metformin, resveratrol, and rapamycin.
Le Couteur DG, Solon-Biet SM, Parker BL, Pulpitel T, Brandon AE, Hunt NJ, Wali JA, Gokarn R, Senior AM, Cooney GJ, Raubenheimer D, Cogger VC, James DE, Simpson SJ. Le Couteur DG, et al. Among authors: cooney gj. Cell Metab. 2021 Dec 7;33(12):2367-2379.e4. doi: 10.1016/j.cmet.2021.10.016. Epub 2021 Nov 11. Cell Metab. 2021. PMID: 34767745 Free article.
209 results