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Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities.
Skoulidis F, Byers LA, Diao L, Papadimitrakopoulou VA, Tong P, Izzo J, Behrens C, Kadara H, Parra ER, Canales JR, Zhang J, Giri U, Gudikote J, Cortez MA, Yang C, Fan Y, Peyton M, Girard L, Coombes KR, Toniatti C, Heffernan TP, Choi M, Frampton GM, Miller V, Weinstein JN, Herbst RS, Wong KK, Zhang J, Sharma P, Mills GB, Hong WK, Minna JD, Allison JP, Futreal A, Wang J, Wistuba II, Heymach JV. Skoulidis F, et al. Among authors: coombes kr. Cancer Discov. 2015 Aug;5(8):860-77. doi: 10.1158/2159-8290.CD-14-1236. Epub 2015 Jun 11. Cancer Discov. 2015. PMID: 26069186 Free PMC article.
Applications of beta-mixture models in bioinformatics.
Ji Y, Wu C, Liu P, Wang J, Coombes KR. Ji Y, et al. Among authors: coombes kr. Bioinformatics. 2005 May 1;21(9):2118-22. doi: 10.1093/bioinformatics/bti318. Epub 2005 Feb 15. Bioinformatics. 2005. PMID: 15713737
Stem cell-ness: a "magic marker" for cancer.
Lahad JP, Mills GB, Coombes KR. Lahad JP, et al. Among authors: coombes kr. J Clin Invest. 2005 Jun;115(6):1463-7. doi: 10.1172/JCI25455. J Clin Invest. 2005. PMID: 15931383 Free PMC article.
Non-parametric quantification of protein lysate arrays.
Hu J, He X, Baggerly KA, Coombes KR, Hennessy BT, Mills GB. Hu J, et al. Among authors: coombes kr. Bioinformatics. 2007 Aug 1;23(15):1986-94. doi: 10.1093/bioinformatics/btm283. Epub 2007 Jun 28. Bioinformatics. 2007. PMID: 17599930
208 results