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An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells.
Colli ML, Ramos-Rodríguez M, Nakayasu ES, Alvelos MI, Lopes M, Hill JLE, Turatsinze JV, Coomans de Brachène A, Russell MA, Raurell-Vila H, Castela A, Juan-Mateu J, Webb-Robertson BM, Krogvold L, Dahl-Jorgensen K, Marselli L, Marchetti P, Richardson SJ, Morgan NG, Metz TO, Pasquali L, Eizirik DL. Colli ML, et al. Among authors: coomans de brachene a. Nat Commun. 2020 May 22;11(1):2584. doi: 10.1038/s41467-020-16327-0. Nat Commun. 2020. PMID: 32444635 Free PMC article.
Checks and Balances-The Limits of β-Cell Endurance to ER Stress.
Eizirik DL, Coomans de Brachène A. Eizirik DL, et al. Among authors: coomans de brachene a. Diabetes. 2017 Jun;66(6):1467-1469. doi: 10.2337/dbi17-0018. Diabetes. 2017. PMID: 28533299 Free PMC article. No abstract available.
PDL1 is expressed in the islets of people with type 1 diabetes and is up-regulated by interferons-α and-γ via IRF1 induction.
Colli ML, Hill JLE, Marroquí L, Chaffey J, Dos Santos RS, Leete P, Coomans de Brachène A, Paula FMM, Op de Beeck A, Castela A, Marselli L, Krogvold L, Dahl-Jorgensen K, Marchetti P, Morgan NG, Richardson SJ, Eizirik DL. Colli ML, et al. Among authors: coomans de brachene a. EBioMedicine. 2018 Oct;36:367-375. doi: 10.1016/j.ebiom.2018.09.040. Epub 2018 Sep 27. EBioMedicine. 2018. PMID: 30269996 Free PMC article.
PDGF-D expression is down-regulated by TGFβ in fibroblasts.
Charni Chaabane S, Coomans de Brachène A, Essaghir A, Velghe A, Lo Re S, Stockis J, Lucas S, Khachigian LM, Huaux F, Demoulin JB. Charni Chaabane S, et al. Among authors: coomans de brachene a. PLoS One. 2014 Oct 3;9(10):e108656. doi: 10.1371/journal.pone.0108656. eCollection 2014. PLoS One. 2014. PMID: 25280005 Free PMC article.
13 results