Cook G - Search Results

1

Discovery of a Natural Product That Binds to the Mycobacterium tuberculosis Protein Rv1466 Using Native Mass Spectrometry.

Elnaas AR, Grice D, Han J, Feng Y, Capua AD, Mak T, Laureanti JA, Buchko GW, Myler PJ, Cook G, Quinn RJ, Liu M. Elnaas AR, et al. Among authors: cook g. Molecules. 2020 May 21;25(10):2384. doi: 10.3390/molecules25102384. Molecules. 2020. PMID: 32455540 Free PMC article.

2

Utilization of CRISPR Interference To Validate MmpL3 as a Drug Target in Mycobacterium tuberculosis.

McNeil MB, Cook GM. McNeil MB, et al. Antimicrob Agents Chemother. 2019 Jul 25;63(8):e00629-19. doi: 10.1128/AAC.00629-19. Print 2019 Aug. Antimicrob Agents Chemother. 2019. PMID: 31160289 Free PMC article.

3

Predicting nitroimidazole antibiotic resistance mutations in Mycobacterium tuberculosis with protein engineering.

Lee BM, Harold LK, Almeida DV, Afriat-Jurnou L, Aung HL, Forde BM, Hards K, Pidot SJ, Ahmed FH, Mohamed AE, Taylor MC, West NP, Stinear TP, Greening C, Beatson SA, Nuermberger EL, Cook GM, Jackson CJ. Lee BM, et al. PLoS Pathog. 2020 Feb 7;16(2):e1008287. doi: 10.1371/journal.ppat.1008287. eCollection 2020 Feb. PLoS Pathog. 2020. PMID: 32032366 Free PMC article.

4

Bridging the gap between a TB drug and its target.

Cook GM, Heikal A. Cook GM, et al. Sci Transl Med. 2012 Sep 5;4(150):150fs33. doi: 10.1126/scitranslmed.3004816. Sci Transl Med. 2012. PMID: 22956196

5

Characterization of the proline-utilization pathway in Mycobacterium tuberculosis through structural and functional studies.

Lagautriere T, Bashiri G, Paterson NG, Berney M, Cook GM, Baker EN. Lagautriere T, et al. Among authors: cook gm. Acta Crystallogr D Biol Crystallogr. 2014 Apr;70(Pt 4):968-80. doi: 10.1107/S1399004713034391. Epub 2014 Mar 19. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 24699642

6

Incorporation of triphenylphosphonium functionality improves the inhibitory properties of phenothiazine derivatives in Mycobacterium tuberculosis.

Dunn EA, Roxburgh M, Larsen L, Smith RA, McLellan AD, Heikal A, Murphy MP, Cook GM. Dunn EA, et al. Bioorg Med Chem. 2014 Oct 1;22(19):5320-8. doi: 10.1016/j.bmc.2014.07.050. Epub 2014 Aug 7. Bioorg Med Chem. 2014. PMID: 25150092

7

Succinate dehydrogenase is the regulator of respiration in Mycobacterium tuberculosis.

Hartman T, Weinrick B, Vilchèze C, Berney M, Tufariello J, Cook GM, Jacobs WR Jr. Hartman T, et al. PLoS Pathog. 2014 Nov 20;10(11):e1004510. doi: 10.1371/journal.ppat.1004510. eCollection 2014 Nov. PLoS Pathog. 2014. PMID: 25412183 Free PMC article.

8

Development of a Mycobacterium smegmatis transposon mutant array for characterising the mechanism of action of tuberculosis drugs: Findings with isoniazid and its structural analogues.

Campen RL, Ackerley DF, Cook GM, O'Toole RF. Campen RL, et al. Tuberculosis (Edinb). 2015 Jul;95(4):432-9. doi: 10.1016/j.tube.2015.03.012. Epub 2015 Apr 17. Tuberculosis (Edinb). 2015. PMID: 25936537

9

Activation of type II NADH dehydrogenase by quinolinequinones mediates antitubercular cell death.

Heikal A, Hards K, Cheung CY, Menorca A, Timmer MS, Stocker BL, Cook GM. Heikal A, et al. J Antimicrob Chemother. 2016 Oct;71(10):2840-7. doi: 10.1093/jac/dkw244. Epub 2016 Jun 30. J Antimicrob Chemother. 2016. PMID: 27365187

10

Whole-genome sequencing of multidrug-resistant Mycobacterium tuberculosis isolates from Myanmar.

Aung HL, Tun T, Moradigaravand D, Köser CU, Nyunt WW, Aung ST, Lwin T, Thinn KK, Crump JA, Parkhill J, Peacock SJ, Cook GM, Hill PC. Aung HL, et al. J Glob Antimicrob Resist. 2016 Sep;6:113-117. doi: 10.1016/j.jgar.2016.04.008. Epub 2016 May 30. J Glob Antimicrob Resist. 2016. PMID: 27530852 Free PMC article.

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