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Structure activity relationship (SAR) study identifies a quinoxaline urea analog that modulates IKKβ phosphorylation for pancreatic cancer therapy.
Sagar S, Singh S, Mallareddy JR, Sonawane YA, Napoleon JV, Rana S, Contreras JI, Rajesh C, Ezell EL, Kizhake S, Garrison JC, Radhakrishnan P, Natarajan A. Sagar S, et al. Among authors: contreras ji. Eur J Med Chem. 2021 Oct 15;222:113579. doi: 10.1016/j.ejmech.2021.113579. Epub 2021 May 30. Eur J Med Chem. 2021. PMID: 34098465 Free PMC article.
Correction: Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy.
Robb CM, Kour S, Contreras JI, Agarwal E, Barger CJ, Rana S, Sonawane Y, Neilsen BK, Taylor M, Kizhake S, Thakare RN, Chowdhury S, Wang J, Black JD, Hollingsworth MA, Brattain MG, Natarajan A. Robb CM, et al. Among authors: contreras ji. Oncotarget. 2020 Jun 23;11(25):2462-2463. doi: 10.18632/oncotarget.27403. eCollection 2020 Jun 23. Oncotarget. 2020. PMID: 32637035 Free PMC article.
Symbiotic prodrugs (SymProDs) dual targeting of NFkappaB and CDK.
Rana S, Kour S, Sonawane YA, Robb CM, Contreras JI, Kizhake S, Zahid M, Karpf AR, Natarajan A. Rana S, et al. Among authors: contreras ji. Chem Biol Drug Des. 2020 Aug;96(2):773-784. doi: 10.1111/cbdd.13684. Epub 2020 Apr 22. Chem Biol Drug Des. 2020. PMID: 32237047 Free PMC article.
Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy.
Robb CM, Kour S, Contreras JI, Agarwal E, Barger CJ, Rana S, Sonawane Y, Neilsen BK, Taylor M, Kizhake S, Thakare RN, Chowdhury S, Wang J, Black JD, Hollingsworth MA, Brattain MG, Natarajan A. Robb CM, et al. Among authors: contreras ji. Oncotarget. 2017 Dec 28;9(4):5216-5232. doi: 10.18632/oncotarget.23749. eCollection 2018 Jan 12. Oncotarget. 2017. PMID: 29435174 Free PMC article.
19 results