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Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells.
Lopez-Sambrooks C, Shrimal S, Khodier C, Flaherty DP, Rinis N, Charest JC, Gao N, Zhao P, Wells L, Lewis TA, Lehrman MA, Gilmore R, Golden JE, Contessa JN. Lopez-Sambrooks C, et al. Nat Chem Biol. 2016 Dec;12(12):1023-1030. doi: 10.1038/nchembio.2194. Epub 2016 Oct 3. Nat Chem Biol. 2016. PMID: 27694802 Free PMC article.
Targeting STT3A-oligosaccharyltransferase with NGI-1 causes herpes simplex virus 1 dysfunction.
Lu H, Cherepanova NA, Gilmore R, Contessa JN, Lehrman MA. Lu H, et al. FASEB J. 2019 Jun;33(6):6801-6812. doi: 10.1096/fj.201802044RR. Epub 2019 Feb 27. FASEB J. 2019. PMID: 30811219 Free PMC article.
Ablation of post-translational N-glycosylation can therefore make HSV-1 infectivity, and possibly masking of immunogenic peptide epitopes by glycans, highly sensitive to pharmacological inhibition of cotranslational N-glycosylation.-Lu, H., Cherepanova, N. A., Gilmore, R., Con …
Ablation of post-translational N-glycosylation can therefore make HSV-1 infectivity, and possibly masking of immunogenic peptide epitopes by …
86 results