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The Role of Gender-specific Cytokine Pathways as Drug Targets and Gender- specific Biomarkers in Personalized Cancer Therapy.
Berghella AM, Contasta I, Lattanzio R, Di Gregorio G, Campitelli I, Silvino M, Liberatore LL, Navarra L, Caterino G, Mongelli A, Vittorini V, Basta M, Domenicucci M, Antonucci N, Del Beato T, Secinaro E, Ciccone F, Pellegrini P. Berghella AM, et al. Among authors: contasta i. Curr Drug Targets. 2017;18(4):485-495. doi: 10.2174/1389450117666160630173647. Curr Drug Targets. 2017. PMID: 27397062
Simultaneous measurement of soluble carcinoembryonic antigen and the tissue inhibitor of metalloproteinase TIMP1 serum levels for use as markers of pre-invasive to invasive colorectal cancer.
Pellegrini P, Contasta I, Berghella AM, Gargano E, Mammarella C, Adorno D. Pellegrini P, et al. Among authors: contasta i. Cancer Immunol Immunother. 2000 Sep;49(7):388-94. doi: 10.1007/s002620000129. Cancer Immunol Immunother. 2000. PMID: 10999465 Free PMC article.
CD30 antigen and multiple sclerosis: CD30, an important costimulatory molecule and marker of a regulatory subpopulation of dendritic cells, is involved in the maintenance of the physiological balance between TH1/TH2 immune responses and tolerance. The role of IFNbeta-1a in the treatment of multiple sclerosis.
Pellegrini P, Totaro R, Contasta I, Berghella AM, Carolei A, Adorno D. Pellegrini P, et al. Among authors: contasta i. Neuroimmunomodulation. 2005;12(4):220-34. doi: 10.1159/000085654. Neuroimmunomodulation. 2005. PMID: 15990453
The discovery of how gender influences age immunological mechanisms in health and disease, and the identification of ageing gender-specific biomarkers, could lead to specifically tailored treatment and ultimately improve therapeutic success rates.
Berghella AM, Contasta I, Del Beato T, Pellegrini P. Berghella AM, et al. Among authors: contasta i. Immun Ageing. 2012 Nov 13;9(1):24. doi: 10.1186/1742-4933-9-24. Immun Ageing. 2012. PMID: 23148571 Free PMC article.
26 results