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Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex.
Calabrese DR, Chen X, Leon EC, Gaikwad SM, Phyo Z, Hewitt WM, Alden S, Hilimire TA, He F, Michalowski AM, Simmons JK, Saunders LB, Zhang S, Connors D, Walters KJ, Mock BA, Schneekloth JS Jr. Calabrese DR, et al. Among authors: connors d. Nat Commun. 2018 Oct 12;9(1):4229. doi: 10.1038/s41467-018-06315-w. Nat Commun. 2018. PMID: 30315240 Free PMC article.
Cooperative Targets of Combined mTOR/HDAC Inhibition Promote MYC Degradation.
Simmons JK, Michalowski AM, Gamache BJ, DuBois W, Patel J, Zhang K, Gary J, Zhang S, Gaikwad S, Connors D, Watson N, Leon E, Chen JQ, Kuehl WM, Lee MP, Zingone A, Landgren O, Ordentlich P, Huang J, Mock BA. Simmons JK, et al. Among authors: connors d. Mol Cancer Ther. 2017 Sep;16(9):2008-2021. doi: 10.1158/1535-7163.MCT-17-0171. Epub 2017 May 18. Mol Cancer Ther. 2017. PMID: 28522584 Free PMC article.
HTS driven by fluorescence lifetime detection of FRET identifies activators and inhibitors of cardiac myosin.
Muretta JM, Rajasekaran D, Blat Y, Little S, Myers M, Nair C, Burdekin B, Yuen SL, Jimenez N, Guhathakurta P, Wilson A, Thompson AR, Surti N, Connors D, Chase P, Harden D, Barbieri CM, Adam L, Thomas DD. Muretta JM, et al. Among authors: connors d. SLAS Discov. 2023 Jul;28(5):223-232. doi: 10.1016/j.slasd.2023.06.001. Epub 2023 Jun 10. SLAS Discov. 2023. PMID: 37307989 Free PMC article.
Reverse Engineering of Digital Measures: Inviting Patients to the Conversation.
Clay I, Peerenboom N, Connors DE, Bourke S, Keogh A, Wac K, Gur-Arie T, Baker J, Bull C, Cereatti A, Cormack F, Eggenspieler D, Foschini L, Ganea R, Groenen PMA, Gusset N, Izmailova E, Kanzler CM, Leyens L, Lyden K, Mueller A, Nam J, Ng WF, Nobbs D, Orfaniotou F, Perumal TM, Piwko W, Ries A, Scotland A, Taptiklis N, Torous J, Vereijken B, Xu S, Baltzer L, Vetter T, Goldhahn J, Hoffmann SC. Clay I, et al. Among authors: connors de. Digit Biomark. 2023 May 12;7(1):28-44. doi: 10.1159/000530413. eCollection 2023 Jan-Dec. Digit Biomark. 2023. PMID: 37206894 Free PMC article.
Case Studies for Overcoming Challenges in Using Big Data in Cancer.
Sweeney SM, Hamadeh HK, Abrams N, Adam SJ, Brenner S, Connors DE, Davis GJ, Fiore LD, Gawel SH, Grossman RL, Hanlon SE, Hsu K, Kelloff GJ, Kirsch IR, Louv B, McGraw D, Meng F, Milgram D, Miller RS, Morgan E, Mukundan L, O'Brien T, Robbins P, Rubin EH, Rubinstein WS, Salmi L, Schaller TH, Shi G, Sigman CC, Srivastava S. Sweeney SM, et al. Among authors: connors de. Cancer Res. 2023 Apr 14;83(8):1183-1190. doi: 10.1158/0008-5472.CAN-22-1277. Cancer Res. 2023. PMID: 36625851 Free PMC article. Review.
Challenges to Using Big Data in Cancer.
Sweeney SM, Hamadeh HK, Abrams N, Adam SJ, Brenner S, Connors DE, Davis GJ, Fiore L, Gawel SH, Grossman RL, Hanlon SE, Hsu K, Kelloff GJ, Kirsch IR, Louv B, McGraw D, Meng F, Milgram D, Miller RS, Morgan E, Mukundan L, O'Brien T, Robbins P, Rubin EH, Rubinstein WS, Salmi L, Schaller T, Shi G, Sigman CC, Srivastava S. Sweeney SM, et al. Among authors: connors de. Cancer Res. 2023 Apr 14;83(8):1175-1182. doi: 10.1158/0008-5472.CAN-22-1274. Cancer Res. 2023. PMID: 36625843 Free PMC article. Review.
62 results