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Page 1
Methazolamide is a new hepatic insulin sensitizer that lowers blood glucose in vivo.
Konstantopoulos N, Molero JC, McGee SL, Spolding B, Connor T, de Vries M, Wanyonyi S, Fahey R, Morrison S, Swinton C, Jones S, Cooper A, Garcia-Guerra L, Foletta VC, Krippner G, Andrikopoulos S, Walder KR. Konstantopoulos N, et al. Among authors: connor t. Diabetes. 2012 Aug;61(8):2146-54. doi: 10.2337/db11-0578. Epub 2012 May 14. Diabetes. 2012. PMID: 22586591 Free PMC article.
Activating HSP72 in rodent skeletal muscle increases mitochondrial number and oxidative capacity and decreases insulin resistance.
Henstridge DC, Bruce CR, Drew BG, Tory K, Kolonics A, Estevez E, Chung J, Watson N, Gardner T, Lee-Young RS, Connor T, Watt MJ, Carpenter K, Hargreaves M, McGee SL, Hevener AL, Febbraio MA. Henstridge DC, et al. Among authors: connor t. Diabetes. 2014 Jun;63(6):1881-94. doi: 10.2337/db13-0967. Epub 2014 Jan 15. Diabetes. 2014. PMID: 24430435 Free PMC article.
Disruption of the Class IIa HDAC Corepressor Complex Increases Energy Expenditure and Lipid Oxidation.
Gaur V, Connor T, Sanigorski A, Martin SD, Bruce CR, Henstridge DC, Bond ST, McEwen KA, Kerr-Bayles L, Ashton TD, Fleming C, Wu M, Pike Winer LS, Chen D, Hudson GM, Schwabe JWR, Baar K, Febbraio MA, Gregorevic P, Pfeffer FM, Walder KR, Hargreaves M, McGee SL. Gaur V, et al. Among authors: connor t. Cell Rep. 2016 Sep 13;16(11):2802-2810. doi: 10.1016/j.celrep.2016.08.005. Cell Rep. 2016. PMID: 27626651 Free article.
Scriptaid enhances skeletal muscle insulin action and cardiac function in obese mice.
Gaur V, Connor T, Venardos K, Henstridge DC, Martin SD, Swinton C, Morrison S, Aston-Mourney K, Gehrig SM, van Ewijk R, Lynch GS, Febbraio MA, Steinberg GR, Hargreaves M, Walder KR, McGee SL. Gaur V, et al. Among authors: connor t. Diabetes Obes Metab. 2017 Jul;19(7):936-943. doi: 10.1111/dom.12896. Epub 2017 Mar 3. Diabetes Obes Metab. 2017. PMID: 28155245
Lysine post-translational modification of glyceraldehyde-3-phosphate dehydrogenase regulates hepatic and systemic metabolism.
Bond ST, Howlett KF, Kowalski GM, Mason S, Connor T, Cooper A, Streltsov V, Bruce CR, Walder KR, McGee SL. Bond ST, et al. Among authors: connor t. FASEB J. 2017 Jun;31(6):2592-2602. doi: 10.1096/fj.201601215R. Epub 2017 Mar 3. FASEB J. 2017. PMID: 28258188
These findings show that post-translational modification of GAPDH lysine residues regulates hepatic and systemic metabolism, revealing an unappreciated role for hepatic GAPDH in substrate selection and utilization.-Bond, S. T., Howlett, K. F., Kowalski, G. M., Mason, S., …
These findings show that post-translational modification of GAPDH lysine residues regulates hepatic and systemic metabolism, revealing an un …
Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice.
Wali JA, Galic S, Tan CY, Gurzov EN, Frazier AE, Connor T, Ge J, Pappas EG, Stroud D, Varanasi LC, Selck C, Ryan MT, Thorburn DR, Kemp BE, Krishnamurthy B, Kay TW, McGee SL, Thomas HE. Wali JA, et al. Among authors: connor t. Cell Death Differ. 2018 Jan;25(1):217-225. doi: 10.1038/cdd.2017.168. Epub 2017 Oct 20. Cell Death Differ. 2018. PMID: 29053141 Free PMC article.
Mechanisms Underpinning the Polypharmacy Effects of Medications in Psychiatry.
Bortolasci CC, Spolding B, Callaly E, Martin S, Panizzutti B, Kidnapillai S, Connor T, Hasebe K, Mohebbi M, Dean OM, McGee SL, Dodd S, Gray L, Berk M, Walder K. Bortolasci CC, et al. Among authors: connor t. Int J Neuropsychopharmacol. 2018 Jun 1;21(6):582-591. doi: 10.1093/ijnp/pyy014. Int J Neuropsychopharmacol. 2018. PMID: 29471411 Free PMC article.
617 results