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Synergistic anti-tumor activity of a novel immunomodulator, BCH-1393, in combination with cyclophosphamide.
Kadhim S, Penney C, Lagraoui M, Heibein J, Attardo G, Zacharie B, Connolly T, Gagnon L. Kadhim S, et al. Among authors: connolly t. Int J Immunopharmacol. 2000 Sep;22(9):659-71. doi: 10.1016/s0192-0561(00)00028-x. Int J Immunopharmacol. 2000. PMID: 10884587
N,N-dimethylaminopurine pentoxycarbonyl D-arginine (BCH-1393) is a novel low molecular weight synthetic immunomodulator that has been shown to significantly stimulate cytotoxic T-lymphocyte responses both in vitro and in vivo (Zacharie B, Gagnon L, Attardo G, Connolly …
N,N-dimethylaminopurine pentoxycarbonyl D-arginine (BCH-1393) is a novel low molecular weight synthetic immunomodulator that has been shown …
Synthesis and activity of a C-8 keto pleuromutilin derivative.
Springer DM, Sorenson ME, Huang S, Connolly TP, Bronson JJ, Matson JA, Hanson RL, Brzozowski DB, LaPorte TL, Patel RN. Springer DM, et al. Bioorg Med Chem Lett. 2003 May 19;13(10):1751-3. doi: 10.1016/s0960-894x(03)00297-x. Bioorg Med Chem Lett. 2003. PMID: 12729657
Synthesis and antibacterial activity of nocathiacin I analogues.
Naidu BN, Sorenson ME, Matiskella JD, Li W, Sausker JB, Zhang Y, Connolly TP, Lam KS, Bronson JJ, Pucci MJ, Yang H, Ueda Y. Naidu BN, et al. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3545-9. doi: 10.1016/j.bmcl.2006.03.079. Epub 2006 Apr 18. Bioorg Med Chem Lett. 2006. PMID: 16621551
Structure-based amelioration of PXR transactivation in a novel series of macrocyclic allosteric inhibitors of HIV-1 integrase.
Sivaprakasam P, Wang Z, Meanwell NA, Khan JA, Langley DR, Johnson SR, Li G, Pendri A, Connolly TP, Gao M, Camac DM, Klakouski C, Zvyaga T, Cianci C, McAuliffe B, Ding B, Discotto L, Krystal MR, Jenkins S, Peese KM, Narasimhulu Naidu B. Sivaprakasam P, et al. Among authors: connolly tp. Bioorg Med Chem Lett. 2020 Nov 15;30(22):127531. doi: 10.1016/j.bmcl.2020.127531. Epub 2020 Sep 2. Bioorg Med Chem Lett. 2020. PMID: 32890685
Phosphonooxymethyl prodrugs of the broad spectrum antifungal azole, ravuconazole: synthesis and biological properties.
Ueda Y, Matiskella JD, Golik J, Connolly TP, Hudyma TW, Venkatesh S, Dali M, Kang SH, Barbour N, Tejwani R, Varia S, Knipe J, Zheng M, Mathew M, Mosure K, Clark J, Lamb L, Medin I, Gao Q, Huang S, Chen CP, Bronson JJ. Ueda Y, et al. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3669-72. doi: 10.1016/j.bmcl.2003.08.029. Bioorg Med Chem Lett. 2003. PMID: 14552754
264 results