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RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD.
Van Eeckhoutte HP, Donovan C, Kim RY, Conlon TM, Ansari M, Khan H, Jayaraman R, Hansbro NG, Dondelinger Y, Delanghe T, Beal AM, Geddes B, Bertin J, Vanden Berghe T, De Volder J, Maes T, Vandenabeele P, Vanaudenaerde BM, Deforce D, Škevin S, Van Nieuwerburgh F, Verhamme FM, Joos GF, Idrees S, Schiller HB, Yildirim AÖ, Faiz A, Bertrand MJM, Brusselle GG, Hansbro PM, Bracke KR. Van Eeckhoutte HP, et al. Among authors: conlon tm. Eur Respir J. 2023 Apr 1;61(4):2201506. doi: 10.1183/13993003.01506-2022. Print 2023 Apr. Eur Respir J. 2023. PMID: 36549711
Small Airway Disease in Pre-Chronic Obstructive Pulmonary Disease with Emphysema: A Cross-Sectional Study.
Verleden SE, Hendriks JMH, Snoeckx A, Mai C, Mentens Y, Callebaut W, De Belie B, Van Schil PE, Verplancke V, Janssens A, Jacob J, Pakzad A, Conlon TM, Guvenc G, Yildirim AÖ, Pauwels P, Koljenovic S, Kwakkel-Van Erp JM, Lapperre TS. Verleden SE, et al. Among authors: conlon tm. Am J Respir Crit Care Med. 2024 Mar 15;209(6):683-692. doi: 10.1164/rccm.202301-0132OC. Am J Respir Crit Care Med. 2024. PMID: 38055196
Aqp5-/- mice exhibit reduced maximal body O2 consumption under cold exposure, normal pulmonary gas exchange, and impaired formation of brown adipose tissue.
Al-Samir S, Yildirim AÖ, Sidhaye VK, King LS, Breves G, Conlon TM, Stoeger C, Gailus-Durner V, Fuchs H, Hrabé de Angelis M, Gros G, Endeward V. Al-Samir S, et al. Among authors: conlon tm. Am J Physiol Regul Integr Comp Physiol. 2023 Jan 1;324(1):R109-R119. doi: 10.1152/ajpregu.00130.2022. Epub 2022 Nov 21. Am J Physiol Regul Integr Comp Physiol. 2023. PMID: 36409022 Free article.
Systems toxicology of complex wood combustion aerosol reveals gaseous carbonyl compounds as critical constituents.
Dilger M, Armant O, Ramme L, Mülhopt S, Sapcariu SC, Schlager C, Dilger E, Reda A, Orasche J, Schnelle-Kreis J, Conlon TM, Yildirim AÖ, Hartwig A, Zimmermann R, Hiller K, Diabaté S, Paur HR, Weiss C. Dilger M, et al. Among authors: conlon tm. Environ Int. 2023 Sep;179:108169. doi: 10.1016/j.envint.2023.108169. Epub 2023 Aug 24. Environ Int. 2023. PMID: 37688811 Free article.
A transcriptomics-guided drug target discovery strategy identifies receptor ligands for lung regeneration.
Wu X, Bos IST, Conlon TM, Ansari M, Verschut V, van der Koog L, Verkleij LA, D'Ambrosi A, Matveyenko A, Schiller HB, Königshoff M, Schmidt M, Kistemaker LEM, Yildirim AÖ, Gosens R. Wu X, et al. Among authors: conlon tm. Sci Adv. 2022 Mar 25;8(12):eabj9949. doi: 10.1126/sciadv.abj9949. Epub 2022 Mar 23. Sci Adv. 2022. PMID: 35319981 Free PMC article.
The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD.
Günes Günsel G, Conlon TM, Jeridi A, Kim R, Ertüz Z, Lang NJ, Ansari M, Novikova M, Jiang D, Strunz M, Gaianova M, Hollauer C, Gabriel C, Angelidis I, Doll S, Pestoni JC, Edelmann SL, Kohlhepp MS, Guillot A, Bassler K, Van Eeckhoutte HP, Kayalar Ö, Konyalilar N, Kanashova T, Rodius S, Ballester-López C, Genes Robles CM, Smirnova N, Rehberg M, Agarwal C, Krikki I, Piavaux B, Verleden SE, Vanaudenaerde B, Königshoff M, Dittmar G, Bracke KR, Schultze JL, Watz H, Eickelberg O, Stoeger T, Burgstaller G, Tacke F, Heissmeyer V, Rinkevich Y, Bayram H, Schiller HB, Conrad M, Schneider R, Yildirim AÖ. Günes Günsel G, et al. Among authors: conlon tm. Nat Commun. 2022 Mar 14;13(1):1303. doi: 10.1038/s41467-022-28809-4. Nat Commun. 2022. PMID: 35288557 Free PMC article.
Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice.
Spix B, Butz ES, Chen CC, Rosato AS, Tang R, Jeridi A, Kudrina V, Plesch E, Wartenberg P, Arlt E, Briukhovetska D, Ansari M, Günsel GG, Conlon TM, Wyatt A, Wetzel S, Teupser D, Holdt LM, Ectors F, Boekhoff I, Boehm U, García-Añoveros J, Saftig P, Giera M, Kobold S, Schiller HB, Zierler S, Gudermann T, Wahl-Schott C, Bracher F, Yildirim AÖ, Biel M, Grimm C. Spix B, et al. Among authors: conlon tm. Nat Commun. 2022 Jan 14;13(1):318. doi: 10.1038/s41467-021-27860-x. Nat Commun. 2022. PMID: 35031603 Free PMC article.
40 results