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Showing results for conhoh j
Search for Conhoc J instead (1 results)
Highly efficient poly(6-acryloylamino-N-hydroxyhexanamide) resin for adsorption of heavy metal ions.
Duan G, Cao Z, Zhong H, Ma X, Wang S. Duan G, et al. J Environ Manage. 2022 Apr 15;308:114631. doi: 10.1016/j.jenvman.2022.114631. Epub 2022 Feb 5. J Environ Manage. 2022. PMID: 35131706
It was revealed that the PAHHA resin possessed multiple active sites, including -CONHOH, -CONH- and -COOH, which could strongly adsorb the metal ions. Specifically, the -CONHOH group displayed a high affinity by forming a stable five-membered ring with heavy metal i …
It was revealed that the PAHHA resin possessed multiple active sites, including -CONHOH, -CONH- and -COOH, which could strongly adsor …
Protease inhibitors. Part 7. Inhibition of Clostridium histolyticum collagenase with sulfonylated derivatives of L-valine hydroxamate.
Supuran CT, Scozzafava A. Supuran CT, et al. Eur J Pharm Sci. 2000 Mar;10(1):67-76. doi: 10.1016/s0928-0987(99)00090-1. Eur J Pharm Sci. 2000. PMID: 10699384
Sulfonylated L-valine hydroxamate derivatives were obtained by reaction of alkyl/arylsulfonyl halides with the title amino acid, followed by treatment with benzyl chloride, and conversion of the COOH moiety to the CONHOH group. Other derivatives were obtained by reaction o …
Sulfonylated L-valine hydroxamate derivatives were obtained by reaction of alkyl/arylsulfonyl halides with the title amino acid, followed by …
Protease inhibitors. Part 12. Synthesis of potent matrix metalloproteinase and bacterial collagenase inhibitors incorporating sulfonylated N-4-nitrobenzyl-beta-alanine hydroxamate moieties.
Scozzafava A, Ilies MA, Manole G, Supuran CT. Scozzafava A, et al. Eur J Pharm Sci. 2000 Jul;11(1):69-79. doi: 10.1016/s0928-0987(00)00089-0. Eur J Pharm Sci. 2000. PMID: 10913755
N-4-Nitrobenzyl-beta-alanine was reacted with alkyl/arylsulfonyl halides, followed by conversion of the COOH to the CONHOH group. Structurally related compounds were obtained by reaction of N-4-nitrobenzyl-beta-alanine with aryl isocyanates, arylsulfonyl isocyanates or ben …
N-4-Nitrobenzyl-beta-alanine was reacted with alkyl/arylsulfonyl halides, followed by conversion of the COOH to the CONHOH group. Str …
Computational investigations on acceptor substituent influence of metal-free efficient chromophores for optoelectronic properties.
Ammasi A, Munusamy AP, Shkir M. Ammasi A, et al. J Mol Model. 2022 Oct 10;28(11):349. doi: 10.1007/s00894-022-05346-x. J Mol Model. 2022. PMID: 36214920
In this study, the computational studies of the PO(3)H(2), CONHOH, and SO(2)H (A1-A3) molecules were investigated for optoelectronic applications on the basis of tetrahydroquinoline (C1-1) dye. ...
In this study, the computational studies of the PO(3)H(2), CONHOH, and SO(2)H (A1-A3) molecules were investigated for optoelectronic …
Protease inhibitors: synthesis of potent bacterial collagenase and matrix metalloproteinase inhibitors incorporating N-4-nitrobenzylsulfonylglycine hydroxamate moieties.
Scozzafava A, Supuran CT. Scozzafava A, et al. J Med Chem. 2000 May 4;43(9):1858-65. doi: 10.1021/jm990594k. J Med Chem. 2000. PMID: 10794702
A series of compounds was prepared by reaction of alkyl/arylsulfonyl halides with N-4-nitrobenzylglycine, followed by conversion of the COOH to the CONHOH group, with hydroxylamine in the presence of carbodiimides. Other structurally related compounds were obtained by reac …
A series of compounds was prepared by reaction of alkyl/arylsulfonyl halides with N-4-nitrobenzylglycine, followed by conversion of the COOH …
Protease inhibitors: Synthesis of L-alanine hydroxamate sulfonylated derivatives as inhibitors of clostridium histolyticum collagenase.
Supuran CT, Briganti F, Mincione G, Scozzafava A. Supuran CT, et al. J Enzyme Inhib. 2000;15(2):111-28. doi: 10.1080/14756360009030345. J Enzyme Inhib. 2000. PMID: 10938538
L-alanine hydroxamate derivatives were obtained by reaction of alkyl/arylsulfonyl halides with L-alanine, followed by treatment with benzyl chloride, and conversion of the COOH moiety to the CONHOH group with hydroxylamine in the presence of carbodiimides. Other derivative …
L-alanine hydroxamate derivatives were obtained by reaction of alkyl/arylsulfonyl halides with L-alanine, followed by treatment with benzyl …
Carbon- versus sulphur-based zinc binding groups for carbonic anhydrase inhibitors?
Supuran CT. Supuran CT. J Enzyme Inhib Med Chem. 2018 Dec;33(1):485-495. doi: 10.1080/14756366.2018.1428572. J Enzyme Inhib Med Chem. 2018. PMID: 29390912 Free PMC article.
A set of compounds incorporating carbon-based zinc-binding groups (ZBGs), of the type PhX (X = COOH, CONH(2), CONHNH(2), CONHOH, CONHOMe), and the corresponding derivatives with sulphur(VI)-based ZBGs (X = SO(3)H, SO(2)NH(2), SO(2)NHNH(2), SO(2)NHOH, SO(2)NHOMe) were teste …
A set of compounds incorporating carbon-based zinc-binding groups (ZBGs), of the type PhX (X = COOH, CONH(2), CONHNH(2), CONHOH, CONH …
Study on hydroxamic acids and their urease inhibitory potency by quantum chemistry calculation.
Kanoda M, Shinoda H, Kobashi K, Hase J, Nagahara S. Kanoda M, et al. J Pharmacobiodyn. 1983 Feb;6(2):61-70. doi: 10.1248/bpb1978.6.61. J Pharmacobiodyn. 1983. PMID: 6864441
The electronic structures of 34 hydroxamic acids [R-(CONHCH2(n-CONHOH, R = aromatic or aliphatic, n = 1 or 0] were calculated by the INDO method and their urease inhibitory potencies were discussed in terms of the calculated electronic parameters and molar refraction. The …
The electronic structures of 34 hydroxamic acids [R-(CONHCH2(n-CONHOH, R = aromatic or aliphatic, n = 1 or 0] were calculated by the …
Discovery of first-in-class multi-target adenosine A2A receptor antagonists-carbonic anhydrase IX and XII inhibitors. 8-Amino-6-aryl-2-phenyl-1,2,4-triazolo [4,3-a]pyrazin-3-one derivatives as new potential antitumor agents.
Ceni C, Catarzi D, Varano F, Ben DD, Marucci G, Buccioni M, Volpini R, Angeli A, Nocentini A, Gratteri P, Supuran CT, Colotta V. Ceni C, et al. Eur J Med Chem. 2020 Sep 1;201:112478. doi: 10.1016/j.ejmech.2020.112478. Epub 2020 Jun 12. Eur J Med Chem. 2020. PMID: 32659606
To address activity against the tumor-associated CA isoforms, it was modified by introduction of different substituents (OH, COOH, CONHOH, SO(2)NH(2)) on the 6-phenyl ring or on a phenyl pendant connected to the former through different spacers. ...
To address activity against the tumor-associated CA isoforms, it was modified by introduction of different substituents (OH, COOH, CONHOH …
Protease inhibitors - part 5. Alkyl/arylsulfonyl- and arylsulfonylureido-/arylureido- glycine hydroxamate inhibitors of Clostridium histolyticum collagenase.
Scozzafava A, Supuran CT. Scozzafava A, et al. Eur J Med Chem. 2000 Mar;35(3):299-307. doi: 10.1016/s0223-5234(00)00127-6. Eur J Med Chem. 2000. PMID: 10785556
Other derivatives were obtained by reaction of N-benzyl-glycine with aryl isocyanates, arylsulfonyl isocyanates or benzoyl isothiocyanate, followed by conversion of their COOH group into the CONHOH moiety, as mentioned above. The 90 new compounds reported here were assayed …
Other derivatives were obtained by reaction of N-benzyl-glycine with aryl isocyanates, arylsulfonyl isocyanates or benzoyl isothiocyanate, f …
23 results