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MITOCHONDRIAL CHOLESTEROL AND CANCER.
Garcia-Ruiz C, Conde de la Rosa L, Ribas V, Fernandez-Checa JC. Garcia-Ruiz C, et al. Among authors: conde de la rosa l. Semin Cancer Biol. 2021 Aug;73:76-85. doi: 10.1016/j.semcancer.2020.07.014. Epub 2020 Aug 14. Semin Cancer Biol. 2021. PMID: 32805396 Free PMC article. Review.
Mitochondrial GSH determines the toxic or therapeutic potential of superoxide scavenging in steatohepatitis.
von Montfort C, Matias N, Fernandez A, Fucho R, Conde de la Rosa L, Martinez-Chantar ML, Mato JM, Machida K, Tsukamoto H, Murphy MP, Mansouri A, Kaplowitz N, Garcia-Ruiz C, Fernandez-Checa JC. von Montfort C, et al. Among authors: conde de la rosa l. J Hepatol. 2012 Oct;57(4):852-9. doi: 10.1016/j.jhep.2012.05.024. Epub 2012 Jun 9. J Hepatol. 2012. PMID: 22687340 Free PMC article.
The 2-oxoglutarate carrier promotes liver cancer by sustaining mitochondrial GSH despite cholesterol loading.
Baulies A, Montero J, Matías N, Insausti N, Terrones O, Basañez G, Vallejo C, Conde de La Rosa L, Martinez L, Robles D, Morales A, Abian J, Carrascal M, Machida K, Kumar DBU, Tsukamoto H, Kaplowitz N, Garcia-Ruiz C, Fernández-Checa JC. Baulies A, et al. Among authors: conde de la rosa l. Redox Biol. 2018 Apr;14:164-177. doi: 10.1016/j.redox.2017.08.022. Epub 2017 Sep 14. Redox Biol. 2018. PMID: 28942194 Free PMC article.
Sphingomyelin synthase 1 mediates hepatocyte pyroptosis to trigger non-alcoholic steatohepatitis.
Koh EH, Yoon JE, Ko MS, Leem J, Yun JY, Hong CH, Cho YK, Lee SE, Jang JE, Baek JY, Yoo HJ, Kim SJ, Sung CO, Lim JS, Jeong WI, Back SH, Baek IJ, Torres S, Solsona-Vilarrasa E, Conde de la Rosa L, Garcia-Ruiz C, Feldstein AE, Fernandez-Checa JC, Lee KU. Koh EH, et al. Among authors: conde de la rosa l. Gut. 2021 Oct;70(10):1954-1964. doi: 10.1136/gutjnl-2020-322509. Epub 2020 Nov 18. Gut. 2021. PMID: 33208407 Free PMC article.
STARD1 promotes NASH-driven HCC by sustaining the generation of bile acids through the alternative mitochondrial pathway.
Conde de la Rosa L, Garcia-Ruiz C, Vallejo C, Baulies A, Nuñez S, Monte MJ, Marin JJG, Baila-Rueda L, Cenarro A, Civeira F, Fuster J, Garcia-Valdecasas JC, Ferrer J, Karin M, Ribas V, Fernandez-Checa JC. Conde de la Rosa L, et al. J Hepatol. 2021 Jun;74(6):1429-1441. doi: 10.1016/j.jhep.2021.01.028. Epub 2021 Jan 27. J Hepatol. 2021. PMID: 33515644 Free PMC article.
Sphingosine 1-Phosphate Receptor 4 Promotes Nonalcoholic Steatohepatitis by Activating NLRP3 Inflammasome.
Hong CH, Ko MS, Kim JH, Cho H, Lee CH, Yoon JE, Yun JY, Baek IJ, Jang JE, Lee SE, Cho YK, Baek JY, Oh SJ, Lee BY, Lim JS, Lee J, Hartig SM, Conde de la Rosa L, Garcia-Ruiz C, Lee KU, Fernández-Checa JC, Choi JW, Kim S, Koh EH. Hong CH, et al. Among authors: conde de la rosa l. Cell Mol Gastroenterol Hepatol. 2022;13(3):925-947. doi: 10.1016/j.jcmgh.2021.12.002. Epub 2021 Dec 8. Cell Mol Gastroenterol Hepatol. 2022. PMID: 34890841 Free PMC article.
Mitochondrial cholesterol: Metabolism and impact on redox biology and disease.
Goicoechea L, Conde de la Rosa L, Torres S, García-Ruiz C, Fernández-Checa JC. Goicoechea L, et al. Among authors: conde de la rosa l. Redox Biol. 2023 May;61:102643. doi: 10.1016/j.redox.2023.102643. Epub 2023 Feb 24. Redox Biol. 2023. PMID: 36857930 Free PMC article. Review.
19 results