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LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons.
Libé-Philippot B, Lejeune A, Wierda K, Louros N, Erkol E, Vlaeminck I, Beckers S, Gaspariunaite V, Bilheu A, Konstantoulea K, Nyitrai H, De Vleeschouwer M, Vennekens KM, Vidal N, Bird TW, Soto DC, Jaspers T, Dewilde M, Dennis MY, Rousseau F, Comoletti D, Schymkowitz J, Theys T, de Wit J, Vanderhaeghen P. Libé-Philippot B, et al. Among authors: comoletti d. Cell. 2023 Dec 21;186(26):5766-5783.e25. doi: 10.1016/j.cell.2023.11.028. Cell. 2023. PMID: 38134874 Free PMC article.
MAIT cells activate dendritic cells to promote TFH cell differentiation and induce humoral immunity.
Pankhurst TE, Buick KH, Lange JL, Marshall AJ, Button KR, Palmer OR, Farrand KJ, Montgomerie I, Bird TW, Mason NC, Kuang J, Compton BJ, Comoletti D, Salio M, Cerundolo V, Quiñones-Mateu ME, Painter GF, Hermans IF, Connor LM. Pankhurst TE, et al. Among authors: comoletti d. Cell Rep. 2023 Apr 25;42(4):112310. doi: 10.1016/j.celrep.2023.112310. Epub 2023 Mar 28. Cell Rep. 2023. PMID: 36989114 Free PMC article.
Incorporation of SARS-CoV-2 spike NTD to RBD protein vaccine improves immunity against viral variants.
Montgomerie I, Bird TW, Palmer OR, Mason NC, Pankhurst TE, Lawley B, Hernández LC, Harfoot R, Authier-Hall A, Anderson DE, Hilligan KL, Buick KH, Mbenza NM, Mittelstädt G, Maxwell S, Sinha S, Kuang J, Subbarao K, Parker EJ, Sher A, Hermans IF, Ussher JE, Quiñones-Mateu ME, Comoletti D, Connor LM; VAANZ Group. Montgomerie I, et al. Among authors: comoletti d. iScience. 2023 Apr 21;26(4):106256. doi: 10.1016/j.isci.2023.106256. Epub 2023 Feb 20. iScience. 2023. PMID: 36845030 Free PMC article.
Analyses of the autism-associated neuroligin-3 R451C mutation in human neurons reveal a gain-of-function synaptic mechanism.
Wang L, Mirabella VR, Dai R, Su X, Xu R, Jadali A, Bernabucci M, Singh I, Chen Y, Tian J, Jiang P, Kwan KY, Pak C, Liu C, Comoletti D, Hart RP, Chen C, Südhof TC, Pang ZP. Wang L, et al. Among authors: comoletti d. Mol Psychiatry. 2022 Oct 24:10.1038/s41380-022-01834-x. doi: 10.1038/s41380-022-01834-x. Online ahead of print. Mol Psychiatry. 2022. PMID: 36280753 Free PMC article.
GPC3-Unc5 receptor complex structure and role in cell migration.
Akkermans O, Delloye-Bourgeois C, Peregrina C, Carrasquero-Ordaz M, Kokolaki M, Berbeira-Santana M, Chavent M, Reynaud F, Raj R, Agirre J, Aksu M, White ES, Lowe E, Ben Amar D, Zaballa S, Huo J, Pakos I, McCubbin PTN, Comoletti D, Owens RJ, Robinson CV, Castellani V, Del Toro D, Seiradake E. Akkermans O, et al. Among authors: comoletti d. Cell. 2022 Oct 13;185(21):3931-3949.e26. doi: 10.1016/j.cell.2022.09.025. Cell. 2022. PMID: 36240740 Free PMC article.
Structure of Reelin repeat 8 and the adjacent C-terminal region.
Turk LS, Currie MJ, Dobson RCJ, Comoletti D. Turk LS, et al. Among authors: comoletti d. Biophys J. 2022 Jul 5;121(13):2526-2537. doi: 10.1016/j.bpj.2022.06.002. Epub 2022 Jun 3. Biophys J. 2022. PMID: 35659645 Free PMC article.
Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca2+ homeostasis and network synchrony via PMCA2/ATP2B2.
Martín-de-Saavedra MD, Dos Santos M, Culotta L, Varea O, Spielman BP, Parnell E, Forrest MP, Gao R, Yoon S, McCoig E, Jalloul HA, Myczek K, Khalatyan N, Hall EA, Turk LS, Sanz-Clemente A, Comoletti D, Lichtenthaler SF, Burgdorf JS, Barbolina MV, Savas JN, Penzes P. Martín-de-Saavedra MD, et al. Among authors: comoletti d. Neuron. 2022 Feb 16;110(4):627-643.e9. doi: 10.1016/j.neuron.2021.11.025. Epub 2021 Dec 17. Neuron. 2022. PMID: 34921780 Free PMC article.
The structure-function relationship of a signaling-competent, dimeric Reelin fragment.
Turk LS, Kuang X, Dal Pozzo V, Patel K, Chen M, Huynh K, Currie MJ, Mitchell D, Dobson RCJ, D'Arcangelo G, Dai W, Comoletti D. Turk LS, et al. Among authors: comoletti d. Structure. 2021 Oct 7;29(10):1156-1170.e6. doi: 10.1016/j.str.2021.05.012. Epub 2021 Jun 4. Structure. 2021. PMID: 34089653 Free article.
61 results