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CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration.
Combadière C, Feumi C, Raoul W, Keller N, Rodéro M, Pézard A, Lavalette S, Houssier M, Jonet L, Picard E, Debré P, Sirinyan M, Deterre P, Ferroukhi T, Cohen SY, Chauvaud D, Jeanny JC, Chemtob S, Behar-Cohen F, Sennlaub F. Combadière C, et al. J Clin Invest. 2007 Oct;117(10):2920-8. doi: 10.1172/JCI31692. J Clin Invest. 2007. PMID: 17909628 Free PMC article.
[Macular degeneration: retinal microglial cells are guilty].
Sennlaub F, Combadière C. Sennlaub F, et al. Among authors: combadiere c. Med Sci (Paris). 2008 Apr;24(4):365-7. doi: 10.1051/medsci/2008244365. Med Sci (Paris). 2008. PMID: 18405632 Free article. French. No abstract available.
CCR2(+) monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice.
Sennlaub F, Auvynet C, Calippe B, Lavalette S, Poupel L, Hu SJ, Dominguez E, Camelo S, Levy O, Guyon E, Saederup N, Charo IF, Rooijen NV, Nandrot E, Bourges JL, Behar-Cohen F, Sahel JA, Guillonneau X, Raoul W, Combadiere C. Sennlaub F, et al. Among authors: combadiere c. EMBO Mol Med. 2013 Nov;5(11):1775-93. doi: 10.1002/emmm.201302692. Epub 2013 Oct 21. EMBO Mol Med. 2013. PMID: 24142887 Free PMC article.
CD36 Deficiency Inhibits Retinal Inflammation and Retinal Degeneration in Cx3cr1 Knockout Mice.
Lavalette S, Conart JB, Touhami S, Roubeix C, Houssier M, Augustin S, Raoul W, Combadière C, Febbraio M, Ong H, Chemtob S, Sahel JA, Delarasse C, Guillonneau X, Sennlaub F. Lavalette S, et al. Among authors: combadiere c. Front Immunol. 2020 Jan 8;10:3032. doi: 10.3389/fimmu.2019.03032. eCollection 2019. Front Immunol. 2020. PMID: 31969887 Free PMC article.
Lipid-bloated subretinal microglial cells are at the origin of drusen appearance in CX3CR1-deficient mice.
Raoul W, Feumi C, Keller N, Lavalette S, Houssier M, Behar-Cohen F, Combadière C, Sennlaub F. Raoul W, et al. Among authors: combadiere c. Ophthalmic Res. 2008;40(3-4):115-9. doi: 10.1159/000119860. Epub 2008 Apr 18. Ophthalmic Res. 2008. PMID: 18421223 Free PMC article.
We demonstrate that the anatomical equivalent of the drusen-like appearance in these mice are lipid-bloated subretinal microglial cells rather than subretinal pigment epithelium deposits [Combadiere C, et al: J Clin Invest 2007;117:2920-2928]....
We demonstrate that the anatomical equivalent of the drusen-like appearance in these mice are lipid-bloated subretinal microglial cells rath …
152 results