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H3.3-G34R Mutation-Mediated Epigenetic Reprogramming Leads to Enhanced Efficacy of Immune Stimulatory Gene Therapy in Pediatric High-Grade Gliomas.
Garcia-Fabiani MB, Haase S, Banerjee K, McClellan B, Zhu Z, Mujeeb A, Li Y, Yu J, Kadiyala P, Taher A, Núñez FJ, Alghamri MS, Comba A, Mendez FM, Nicola Candia AJ, Salazar B, Koschmann C, Nunez FM, Edwards M, Qin T, Sartor MA, Lowenstein PR, Castro MG. Garcia-Fabiani MB, et al. Among authors: comba a. bioRxiv [Preprint]. 2023 Jun 13:2023.06.13.544658. doi: 10.1101/2023.06.13.544658. bioRxiv. 2023. PMID: 37398299 Free PMC article. Preprint.
Generation of 3D ex vivo mouse- and patient-derived glioma explant slice model for integration of confocal time-lapse imaging and spatial analysis.
Comba A, Varela ML, Faisal SM, Abel CC 2nd, Argento AE, Al-Holou WN, Hollon TC, Perelman JD, Dunn PJ, Motsch S, Castro MG, Lowenstein PR. Comba A, et al. STAR Protoc. 2023 Mar 16;4(2):102174. doi: 10.1016/j.xpro.2023.102174. Online ahead of print. STAR Protoc. 2023. PMID: 36930648 Free PMC article.
The explant slice model allows the integration of confocal time-lapse imaging with spatial analysis for studying migration, invasion, and tumor microenvironment, making it a valuable platform for testing effective treatment modalities. For complete details on the use and e …
The explant slice model allows the integration of confocal time-lapse imaging with spatial analysis for studying migration, invasion, and tu …
Combined cytotoxic and immune-stimulatory gene therapy for primary adult high-grade glioma: a phase 1, first-in-human trial.
Umemura Y, Orringer D, Junck L, Varela ML, West MEJ, Faisal SM, Comba A, Heth J, Sagher O, Leung D, Mammoser A, Hervey-Jumper S, Zamler D, Yadav VN, Dunn P, Al-Holou W, Hollon T, Kim MM, Wahl DR, Camelo-Piragua S, Lieberman AP, Venneti S, McKeever P, Lawrence T, Kurokawa R, Sagher K, Altshuler D, Zhao L, Muraszko K, Castro MG, Lowenstein PR. Umemura Y, et al. Among authors: comba a. Lancet Oncol. 2023 Sep;24(9):1042-1052. doi: 10.1016/S1470-2045(23)00347-9. Lancet Oncol. 2023. PMID: 37657463 Clinical Trial.
Epigenetic Reprogramming of Autophagy Drives Mutant IDH1 Glioma Progression and Response to Radiation.
Núñez FJ, Banerjee K, Mujeeb AA, Mauser A, Tronrud CE, Zhu Z, Taher A, Kadiyala P, Carney SV, Garcia-Fabiani MB, Comba A, Alghamri MS, McClellan BL, Faisal SM, Nwosu ZC, Hong HS, Qin T, Sartor MA, Ljungman M, Cheng SY, Appelman HD, Lowenstein PR, Lahann J, Lyssiotis CA, Castro MG. Núñez FJ, et al. Among authors: comba a. bioRxiv [Preprint]. 2024 Mar 13:2024.03.08.584091. doi: 10.1101/2024.03.08.584091. bioRxiv. 2024. PMID: 38559270 Free PMC article. Preprint.
Editorial: Brain cancer pathogenesis and data integration.
Comba A, Li X, Breznik B. Comba A, et al. Front Genet. 2023 Oct 13;14:1298285. doi: 10.3389/fgene.2023.1298285. eCollection 2023. Front Genet. 2023. PMID: 37900188 Free PMC article. No abstract available.
The frequency of Duchenne muscular dystrophy/Becker muscular dystrophy and Pompe disease in children with isolated transaminase elevation: results from the observational VICTORIA study.
Kansu A, Kuloglu Z, Tümgör G, Taşkın DG, Dalgıç B, Çaltepe G, Demirören K, Doğan G, Tuna Kırsaçlıoğlu C, Arslan D, Işık İA, Demir H, Bekem Ö, Şahin Y, Bayrak NA, Selimoğlu MA, Yavuz S, Taşkaya İE, Altay D; VICTORIA Study Group. Kansu A, et al. Front Pediatr. 2023 Sep 25;11:1272177. doi: 10.3389/fped.2023.1272177. eCollection 2023. Front Pediatr. 2023. PMID: 37818166 Free PMC article.
142 results