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Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability.
Tramonti A, Ghatge MS, Babor JT, Musayev FN, di Salvo ML, Barile A, Colotti G, Giorgi A, Paredes SD, Donkor AK, Al Mughram MH, de Crécy-Lagard V, Safo MK, Contestabile R. Tramonti A, et al. Among authors: colotti g. Protein Sci. 2022 Nov;31(11):e4471. doi: 10.1002/pro.4471. Protein Sci. 2022. PMID: 36218140 Free PMC article.
Sorcin promotes migration in cancer and regulates the EGF-dependent EGFR signaling pathways.
Tito C, Genovese I, Giamogante F, Benedetti A, Miglietta S, Barazzuol L, Cristiano L, Iaiza A, Carolini S, De Angelis L, Masciarelli S, Nottola SA, Familiari G, Petrozza V, Lauriola M, Tamagnone L, Ilari A, Calì T, Valdivia HH, Valdivia CR, Colotti G, Fazi F. Tito C, et al. Among authors: colotti g. Cell Mol Life Sci. 2023 Jul 13;80(8):202. doi: 10.1007/s00018-023-04850-4. Cell Mol Life Sci. 2023. PMID: 37442828 Free PMC article.
Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives.
Saccoliti F, Angiulli G, Pupo G, Pescatori L, Madia VN, Messore A, Colotti G, Fiorillo A, Scipione L, Gramiccia M, Di Muccio T, Di Santo R, Costi R, Ilari A. Saccoliti F, et al. Among authors: colotti g. J Enzyme Inhib Med Chem. 2017 Dec;32(1):304-310. doi: 10.1080/14756366.2016.1250755. J Enzyme Inhib Med Chem. 2017. PMID: 28098499 Free PMC article.
Spiro-containing derivatives show antiparasitic activity against Trypanosoma brucei through inhibition of the trypanothione reductase enzyme.
Turcano L, Battista T, De Haro ET, Missineo A, Alli C, Paonessa G, Colotti G, Harper S, Fiorillo A, Ilari A, Bresciani A. Turcano L, et al. Among authors: colotti g. PLoS Negl Trop Dis. 2020 May 21;14(5):e0008339. doi: 10.1371/journal.pntd.0008339. eCollection 2020 May. PLoS Negl Trop Dis. 2020. PMID: 32437349 Free PMC article.
Exogenous peptides are able to penetrate human cell and mitochondrial membranes, stabilize mitochondrial tRNA structures, and rescue severe mitochondrial defects.
Perli E, Pisano A, Pignataro MG, Campese AF, Pelullo M, Genovese I, de Turris V, Ghelli AM, Cerbelli B, Giordano C, Colotti G, Morea V, d'Amati G. Perli E, et al. Among authors: colotti g. FASEB J. 2020 Jun;34(6):7675-7686. doi: 10.1096/fj.201903270R. Epub 2020 Apr 18. FASEB J. 2020. PMID: 32304340
96 results