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Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado-Joseph disease.
Brain. 2011 May;134(Pt 5):1400-15. doi: 10.1093/brain/awr047. Epub 2011 Apr 7.
Brain. 2011.
PMID: 21478185
A mutant ataxin-3 fragment results from processing at a site N-terminal to amino acid 190 in brain of Machado-Joseph disease-like transgenic mice.
Colomer Gould VF, Goti D, Pearce D, Gonzalez GA, Gao H, Bermudez de Leon M, Jenkins NA, Copeland NG, Ross CA, Brown DR.
Colomer Gould VF, et al.
Neurobiol Dis. 2007 Sep;27(3):362-9. doi: 10.1016/j.nbd.2007.06.005. Epub 2007 Jun 13.
Neurobiol Dis. 2007.
PMID: 17632007
Free PMC article.
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Mouse models of spinocerebellar ataxia type 3 (Machado-Joseph disease).
Colomer Gould VF.
Colomer Gould VF.
Neurotherapeutics. 2012 Apr;9(2):285-96. doi: 10.1007/s13311-012-0117-x.
Neurotherapeutics. 2012.
PMID: 22451301
Free PMC article.
Review.
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Mouse models of Machado-Joseph disease and other polyglutamine spinocerebellar ataxias.
Colomer Gould VF.
Colomer Gould VF.
NeuroRx. 2005 Jul;2(3):480-3. doi: 10.1602/neurorx.2.3.480.
NeuroRx. 2005.
PMID: 16389311
Free PMC article.
Review.
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In vivo suppression of polyglutamine neurotoxicity by C-terminus of Hsp70-interacting protein (CHIP) supports an aggregation model of pathogenesis.
Williams AJ, Knutson TM, Colomer Gould VF, Paulson HL.
Williams AJ, et al. Among authors: colomer gould vf.
Neurobiol Dis. 2009 Mar;33(3):342-53. doi: 10.1016/j.nbd.2008.10.016. Epub 2008 Nov 8.
Neurobiol Dis. 2009.
PMID: 19084066
Free PMC article.
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A neuroendocrine dysfunction, not testicular mutant ataxin-3 cleavage fragment or aggregate, causes cell death in testes of transgenic mice.
Colomer Gould VF, Goti D, Kiluk J.
Colomer Gould VF, et al.
Cell Death Differ. 2006 Mar;13(3):524-6. doi: 10.1038/sj.cdd.4401800.
Cell Death Differ. 2006.
PMID: 16282980
No abstract available.
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Incorporation of the pancreatic membrane protein GP-2 into secretory granules in exocrine but not endocrine cells.
Hoops TC, Ivanov I, Cui Z, Colomer-Gould V, Rindler MJ.
Hoops TC, et al.
J Biol Chem. 1993 Dec 5;268(34):25694-705.
J Biol Chem. 1993.
PMID: 7503984
Free article.
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