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Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen.
Miguel-Blanco C, Molina I, Bardera AI, Díaz B, de Las Heras L, Lozano S, González C, Rodrigues J, Delves MJ, Ruecker A, Colmenarejo G, Viera S, Martínez-Martínez MS, Fernández E, Baum J, Sinden RE, Herreros E. Miguel-Blanco C, et al. Among authors: colmenarejo g. Nat Commun. 2017 May 17;8:15160. doi: 10.1038/ncomms15160. Nat Commun. 2017. PMID: 28513586 Free PMC article.
Identification of Selective Inhibitors of Plasmodium N-Myristoyltransferase by High-Throughput Screening.
Harupa A, De Las Heras L, Colmenarejo G, Lyons-Abbott S, Reers A, Caballero Hernandez I, Chung CW, Charter D, Myler PJ, Fernández-Menéndez RM, Calderón F, Palomo S, Rodríguez B, Berlanga M, Herreros-Avilés E, Staker BL, Fernández Álvaro E, Kaushansky A. Harupa A, et al. Among authors: colmenarejo g. J Med Chem. 2020 Jan 23;63(2):591-600. doi: 10.1021/acs.jmedchem.9b01343. Epub 2020 Jan 8. J Med Chem. 2020. PMID: 31850752
Case Study of Small Molecules As Antimalarials: 2-Amino-1-phenylethanol (APE) Derivatives.
Chaparro MJ, Vidal J, Angulo-Barturen I, Bueno JM, Burrows J, Cammack N, Castañeda P, Colmenarejo G, Coterón JM, de Las Heras L, Fernández E, Ferrer S, Gabarró R, Gamo FJ, García M, Jiménez-Díaz MB, Lafuente MJ, León ML, Martínez MS, Minick D, Prats S, Puente M, Rueda L, Sandoval E, Santos-Villarejo A, Witty M, Calderón F. Chaparro MJ, et al. Among authors: colmenarejo g. ACS Med Chem Lett. 2014 Mar 26;5(6):657-61. doi: 10.1021/ml500015r. eCollection 2014 Jun 12. ACS Med Chem Lett. 2014. PMID: 24944739 Free PMC article.
New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites: an open resource.
Peña I, Pilar Manzano M, Cantizani J, Kessler A, Alonso-Padilla J, Bardera AI, Alvarez E, Colmenarejo G, Cotillo I, Roquero I, de Dios-Anton F, Barroso V, Rodriguez A, Gray DW, Navarro M, Kumar V, Sherstnev A, Drewry DH, Brown JR, Fiandor JM, Julio Martin J. Peña I, et al. Among authors: colmenarejo g. Sci Rep. 2015 Mar 5;5:8771. doi: 10.1038/srep08771. Sci Rep. 2015. PMID: 25740547 Free PMC article.
Identification and characterization of hundreds of potent and selective inhibitors of Trypanosoma brucei growth from a kinase-targeted library screening campaign.
Diaz R, Luengo-Arratta SA, Seixas JD, Amata E, Devine W, Cordon-Obras C, Rojas-Barros DI, Jimenez E, Ortega F, Crouch S, Colmenarejo G, Fiandor JM, Martin JJ, Berlanga M, Gonzalez S, Manzano P, Navarro M, Pollastri MP. Diaz R, et al. Among authors: colmenarejo g. PLoS Negl Trop Dis. 2014 Oct 23;8(10):e3253. doi: 10.1371/journal.pntd.0003253. eCollection 2014 Oct. PLoS Negl Trop Dis. 2014. PMID: 25340575 Free PMC article.
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