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Sulindac sulfide as a non-immune suppressive γ-secretase modulator to target triple-negative breast cancer.
Hossain F, Ucar DA, Monticone G, Ran Y, Majumder S, Larter K, Luu H, Wyczechowska D, Heidari S, Xu K, Shanthalingam S, Matossian M, Xi Y, Burow M, Collins-Burow B, Del Valle L, Hicks C, Zabaleta J, Golde T, Osborne B, Miele L. Hossain F, et al. Among authors: collins burow b. Front Immunol. 2023 Oct 13;14:1244159. doi: 10.3389/fimmu.2023.1244159. eCollection 2023. Front Immunol. 2023. PMID: 37901240 Free PMC article.
Notch Signaling Regulates Mitochondrial Metabolism and NF-κB Activity in Triple-Negative Breast Cancer Cells via IKKα-Dependent Non-canonical Pathways.
Hossain F, Sorrentino C, Ucar DA, Peng Y, Matossian M, Wyczechowska D, Crabtree J, Zabaleta J, Morello S, Del Valle L, Burow M, Collins-Burow B, Pannuti A, Minter LM, Golde TE, Osborne BA, Miele L. Hossain F, et al. Front Oncol. 2018 Dec 4;8:575. doi: 10.3389/fonc.2018.00575. eCollection 2018. Front Oncol. 2018. PMID: 30564555 Free PMC article.
Ceritinib is a novel triple negative breast cancer therapeutic agent.
Dong S, Yousefi H, Savage IV, Okpechi SC, Wright MK, Matossian MD, Collins-Burow BM, Burow ME, Alahari SK. Dong S, et al. Among authors: collins burow bm. Mol Cancer. 2022 Jun 29;21(1):138. doi: 10.1186/s12943-022-01601-0. Mol Cancer. 2022. PMID: 35768871 Free PMC article.
A novel patient-derived xenograft model for claudin-low triple-negative breast cancer.
Matossian MD, Burks HE, Bowles AC, Elliott S, Hoang VT, Sabol RA, Pashos NC, O'Donnell B, Miller KS, Wahba BM, Bunnell BA, Moroz K, Zea AH, Jones SD, Ochoa AC, Al-Khami AA, Hossain F, Riker AI, Rhodes LV, Martin EC, Miele L, Burow ME, Collins-Burow BM. Matossian MD, et al. Breast Cancer Res Treat. 2018 Jun;169(2):381-390. doi: 10.1007/s10549-018-4685-2. Epub 2018 Feb 1. Breast Cancer Res Treat. 2018. PMID: 29392581 Free PMC article.
Leptin produced by obesity-altered adipose stem cells promotes metastasis but not tumorigenesis of triple-negative breast cancer in orthotopic xenograft and patient-derived xenograft models.
Sabol RA, Bowles AC, Côté A, Wise R, O'Donnell B, Matossian MD, Hossain FM, Burks HE, Del Valle L, Miele L, Collins-Burow BM, Burow ME, Bunnell BA. Sabol RA, et al. Breast Cancer Res. 2019 May 22;21(1):67. doi: 10.1186/s13058-019-1153-9. Breast Cancer Res. 2019. PMID: 31118047 Free PMC article.
A novel screening approach comparing kinase activity of small molecule inhibitors with similar molecular structures and distinct biologic effects in triple-negative breast cancer to identify targetable signaling pathways.
Matossian MD, Burks HE, Elliott S, Hoang VT, Zuercher WJ, Wells C, Drewry DH, Kapadia N, Chang T, Yan T, Windsor GO, Nguyen K, Fang F, Nephew KP, Buechlein A, Rusch DB, Sabol RA, Ucar DA, Zabaleta J, Miele L, Bunnell BA, Collins-Burow BM, Burow ME. Matossian MD, et al. Anticancer Drugs. 2020 Sep;31(8):759-775. doi: 10.1097/CAD.0000000000000962. Anticancer Drugs. 2020. PMID: 32796402 Free PMC article.
ERK5 Is Required for Tumor Growth and Maintenance Through Regulation of the Extracellular Matrix in Triple Negative Breast Cancer.
Hoang VT, Matossian MD, Ucar DA, Elliott S, La J, Wright MK, Burks HE, Perles A, Hossain F, King CT, Browning VE, Bursavich J, Fang F, Del Valle L, Bhatt AB, Cavanaugh JE, Flaherty PT, Anbalagan M, Rowan BG, Bratton MR, Nephew KP, Miele L, Collins-Burow BM, Martin EC, Burow ME. Hoang VT, et al. Front Oncol. 2020 Aug 3;10:1164. doi: 10.3389/fonc.2020.01164. eCollection 2020. Front Oncol. 2020. PMID: 32850332 Free PMC article.
Evaluation of deacetylase inhibition in metaplastic breast carcinoma using multiple derivations of preclinical models of a new patient-derived tumor.
Chang TC, Matossian MD, Elliott S, Burks HE, Sabol RA, Ucar DA, Wathieu H, Zabaleta J, Del Valle L, Gill S, Martin E, Riker AI, Miele L, Bunnell BA, Burow ME, Collins-Burow BM. Chang TC, et al. PLoS One. 2020 Oct 9;15(10):e0226464. doi: 10.1371/journal.pone.0226464. eCollection 2020. PLoS One. 2020. PMID: 33035223 Free PMC article.
78 results