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An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells.
Colli ML, Ramos-Rodríguez M, Nakayasu ES, Alvelos MI, Lopes M, Hill JLE, Turatsinze JV, Coomans de Brachène A, Russell MA, Raurell-Vila H, Castela A, Juan-Mateu J, Webb-Robertson BM, Krogvold L, Dahl-Jorgensen K, Marselli L, Marchetti P, Richardson SJ, Morgan NG, Metz TO, Pasquali L, Eizirik DL. Colli ML, et al. Nat Commun. 2020 May 22;11(1):2584. doi: 10.1038/s41467-020-16327-0. Nat Commun. 2020. PMID: 32444635 Free PMC article.
STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation.
Moore F, Naamane N, Colli ML, Bouckenooghe T, Ortis F, Gurzov EN, Igoillo-Esteve M, Mathieu C, Bontempi G, Thykjaer T, Ørntoft TF, Eizirik DL. Moore F, et al. Among authors: colli ml. J Biol Chem. 2011 Jan 14;286(2):929-41. doi: 10.1074/jbc.M110.162131. Epub 2010 Oct 27. J Biol Chem. 2011. PMID: 20980260 Free PMC article.
The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines.
Eizirik DL, Sammeth M, Bouckenooghe T, Bottu G, Sisino G, Igoillo-Esteve M, Ortis F, Santin I, Colli ML, Barthson J, Bouwens L, Hughes L, Gregory L, Lunter G, Marselli L, Marchetti P, McCarthy MI, Cnop M. Eizirik DL, et al. Among authors: colli ml. PLoS Genet. 2012;8(3):e1002552. doi: 10.1371/journal.pgen.1002552. Epub 2012 Mar 8. PLoS Genet. 2012. PMID: 22412385 Free PMC article.
41 results