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Integrative functional genomic analysis of human brain development and neuropsychiatric risks.
Li M, Santpere G, Imamura Kawasawa Y, Evgrafov OV, Gulden FO, Pochareddy S, Sunkin SM, Li Z, Shin Y, Zhu Y, Sousa AMM, Werling DM, Kitchen RR, Kang HJ, Pletikos M, Choi J, Muchnik S, Xu X, Wang D, Lorente-Galdos B, Liu S, Giusti-Rodríguez P, Won H, de Leeuw CA, Pardiñas AF; BrainSpan Consortium; PsychENCODE Consortium; PsychENCODE Developmental Subgroup; Hu M, Jin F, Li Y, Owen MJ, O'Donovan MC, Walters JTR, Posthuma D, Reimers MA, Levitt P, Weinberger DR, Hyde TM, Kleinman JE, Geschwind DH, Hawrylycz MJ, State MW, Sanders SJ, Sullivan PF, Gerstein MB, Lein ES, Knowles JA, Sestan N. Li M, et al. Science. 2018 Dec 14;362(6420):eaat7615. doi: 10.1126/science.aat7615. Science. 2018. PMID: 30545854 Free PMC article.
Revealing the brain's molecular architecture.
PsychENCODE Consortium. PsychENCODE Consortium. Science. 2018 Dec 14;362(6420):1262-1263. doi: 10.1126/science.362.6420.1262. Science. 2018. PMID: 30545881 No abstract available.
Transcriptome and epigenome landscape of human cortical development modeled in organoids.
Amiri A, Coppola G, Scuderi S, Wu F, Roychowdhury T, Liu F, Pochareddy S, Shin Y, Safi A, Song L, Zhu Y, Sousa AMM; PsychENCODE Consortium; Gerstein M, Crawford GE, Sestan N, Abyzov A, Vaccarino FM. Amiri A, et al. Science. 2018 Dec 14;362(6420):eaat6720. doi: 10.1126/science.aat6720. Science. 2018. PMID: 30545853 Free PMC article.
Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs.
Burke EE, Chenoweth JG, Shin JH, Collado-Torres L, Kim SK, Micali N, Wang Y, Colantuoni C, Straub RE, Hoeppner DJ, Chen HY, Sellers A, Shibbani K, Hamersky GR, Diaz Bustamante M, Phan BN, Ulrich WS, Valencia C, Jaishankar A, Price AJ, Rajpurohit A, Semick SA, Bürli RW, Barrow JC, Hiler DJ, Page SC, Martinowich K, Hyde TM, Kleinman JE, Berman KF, Apud JA, Cross AJ, Brandon NJ, Weinberger DR, Maher BJ, McKay RDG, Jaffe AE. Burke EE, et al. Nat Commun. 2020 Jan 23;11(1):462. doi: 10.1038/s41467-019-14266-z. Nat Commun. 2020. PMID: 31974374 Free PMC article.
Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk.
Jaffe AE, Hoeppner DJ, Saito T, Blanpain L, Ukaigwe J, Burke EE, Collado-Torres L, Tao R, Tajinda K, Maynard KR, Tran MN, Martinowich K, Deep-Soboslay A, Shin JH, Kleinman JE, Weinberger DR, Matsumoto M, Hyde TM. Jaffe AE, et al. Nat Neurosci. 2020 Apr;23(4):510-519. doi: 10.1038/s41593-020-0604-z. Epub 2020 Mar 16. Nat Neurosci. 2020. PMID: 32203495
Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex.
Maynard KR, Collado-Torres L, Weber LM, Uytingco C, Barry BK, Williams SR, Catallini JL 2nd, Tran MN, Besich Z, Tippani M, Chew J, Yin Y, Kleinman JE, Hyde TM, Rao N, Hicks SC, Martinowich K, Jaffe AE. Maynard KR, et al. Nat Neurosci. 2021 Mar;24(3):425-436. doi: 10.1038/s41593-020-00787-0. Epub 2021 Feb 8. Nat Neurosci. 2021. PMID: 33558695 Free PMC article.
Single-nucleus transcriptome analysis reveals cell-type-specific molecular signatures across reward circuitry in the human brain.
Tran MN, Maynard KR, Spangler A, Huuki LA, Montgomery KD, Sadashivaiah V, Tippani M, Barry BK, Hancock DB, Hicks SC, Kleinman JE, Hyde TM, Collado-Torres L, Jaffe AE, Martinowich K. Tran MN, et al. Neuron. 2021 Oct 6;109(19):3088-3103.e5. doi: 10.1016/j.neuron.2021.09.001. Epub 2021 Sep 27. Neuron. 2021. PMID: 34582785 Free PMC article.
71 results