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Lectin-Like Oxidized Low-Density Lipoprotein Receptor 1 Inhibition in Type 2 Diabetes: Phase 1 Results.
Vavere AL, Sinsakul M, Ongstad EL, Yang Y, Varma V, Jones C, Goodman J, Dubois VFS, Quartino AL, Karathanasis SK, Abuhatzira L, Collén A, Antoniades C, Koren MJ, Gupta R, George RT. Vavere AL, et al. Among authors: collen a. J Am Heart Assoc. 2023 Feb 7;12(3):e027540. doi: 10.1161/JAHA.122.027540. Epub 2023 Jan 23. J Am Heart Assoc. 2023. PMID: 36688371 Free PMC article. Clinical Trial.
Relationship of Soluble Lectin-Like Low-Density Lipoprotein Receptor-1 (sLOX-1) With Inflammation and Coronary Plaque Progression in Psoriasis.
Florida EM, Li H, Hong CG, Ongstad EL, Gaddipati R, Sitaula S, Varma V, Parel PM, O'Hagan R, Chen MY, Teague HL, Playford MP, Karathanasis SK, Collén A, Mehta NN, Remaley AT, Sorokin AV. Florida EM, et al. Among authors: collen a. J Am Heart Assoc. 2023 Nov 20;12(22):e031227. doi: 10.1161/JAHA.123.031227. Online ahead of print. J Am Heart Assoc. 2023. PMID: 37982276 Free PMC article.
Intradermal delivery of modified mRNA encoding VEGF-A in patients with type 2 diabetes.
Gan LM, Lagerström-Fermér M, Carlsson LG, Arfvidsson C, Egnell AC, Rudvik A, Kjaer M, Collén A, Thompson JD, Joyal J, Chialda L, Koernicke T, Fuhr R, Chien KR, Fritsche-Danielson R. Gan LM, et al. Among authors: collen a. Nat Commun. 2019 Feb 20;10(1):871. doi: 10.1038/s41467-019-08852-4. Nat Commun. 2019. PMID: 30787295 Free PMC article.
VEGFA mRNA for regenerative treatment of heart failure.
Collén A, Bergenhem N, Carlsson L, Chien KR, Hoge S, Gan LM, Fritsche-Danielson R. Collén A, et al. Nat Rev Drug Discov. 2022 Jan;21(1):79-80. doi: 10.1038/s41573-021-00355-6. Nat Rev Drug Discov. 2022. PMID: 34873303 Free PMC article. No abstract available.
Novel endosomolytic compounds enable highly potent delivery of antisense oligonucleotides.
Bost JP, Ojansivu M, Munson MJ, Wesén E, Gallud A, Gupta D, Gustafsson O, Saher O, Rädler J, Higgins SG, Lehto T, Holme MN, Dahlén A, Engkvist O, Strömstedt PE, Andersson S, Edvard Smith CI, Stevens MM, Esbjörner EK, Collén A, El Andaloussi S. Bost JP, et al. Among authors: collen a. Commun Biol. 2022 Mar 1;5(1):185. doi: 10.1038/s42003-022-03132-2. Commun Biol. 2022. PMID: 35233031 Free PMC article.
A CRISP(e)R view on kidney organoids allows generation of an induced pluripotent stem cell-derived kidney model for drug discovery.
Boreström C, Jonebring A, Guo J, Palmgren H, Cederblad L, Forslöw A, Svensson A, Söderberg M, Reznichenko A, Nyström J, Patrakka J, Hicks R, Maresca M, Valastro B, Collén A. Boreström C, et al. Among authors: collen a. Kidney Int. 2018 Dec;94(6):1099-1110. doi: 10.1016/j.kint.2018.05.003. Epub 2018 Jul 31. Kidney Int. 2018. PMID: 30072040 Free article.
49 results