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Metformin interferes with bile acid homeostasis through AMPK-FXR crosstalk.
Lien F, Berthier A, Bouchaert E, Gheeraert C, Alexandre J, Porez G, Prawitt J, Dehondt H, Ploton M, Colin S, Lucas A, Patrice A, Pattou F, Diemer H, Van Dorsselaer A, Rachez C, Kamilic J, Groen AK, Staels B, Lefebvre P. Lien F, et al. Among authors: colin s. J Clin Invest. 2014 Mar;124(3):1037-51. doi: 10.1172/JCI68815. Epub 2014 Feb 17. J Clin Invest. 2014. PMID: 24531544 Free PMC article.
Macrophage phenotypes in atherosclerosis.
Colin S, Chinetti-Gbaguidi G, Staels B. Colin S, et al. Immunol Rev. 2014 Nov;262(1):153-66. doi: 10.1111/imr.12218. Immunol Rev. 2014. PMID: 25319333 Review.
Liver X Receptor Regulates Triglyceride Absorption Through Intestinal Down-regulation of Scavenger Receptor Class B, Type 1.
Briand O, Touche V, Colin S, Brufau G, Davalos A, Schonewille M, Bovenga F, Carrière V, de Boer JF, Dugardin C, Riveau B, Clavey V, Tailleux A, Moschetta A, Lasunción MA, Groen AK, Staels B, Lestavel S. Briand O, et al. Among authors: colin s. Gastroenterology. 2016 Mar;150(3):650-8. doi: 10.1053/j.gastro.2015.11.015. Epub 2015 Nov 18. Gastroenterology. 2016. PMID: 26602218
Macrophage subsets in atherosclerosis.
Chinetti-Gbaguidi G, Colin S, Staels B. Chinetti-Gbaguidi G, et al. Among authors: colin s. Nat Rev Cardiol. 2015 Jan;12(1):10-7. doi: 10.1038/nrcardio.2014.173. Epub 2014 Nov 4. Nat Rev Cardiol. 2015. PMID: 25367649 Review.
Emerging small molecule drugs.
Colin S, Chinetti-Gbaguidi G, Kuivenhoven JA, Staels B. Colin S, et al. Handb Exp Pharmacol. 2015;224:617-30. doi: 10.1007/978-3-319-09665-0_20. Handb Exp Pharmacol. 2015. PMID: 25523004 Review.
The novel selective PPARα modulator (SPPARMα) pemafibrate improves dyslipidemia, enhances reverse cholesterol transport and decreases inflammation and atherosclerosis.
Hennuyer N, Duplan I, Paquet C, Vanhoutte J, Woitrain E, Touche V, Colin S, Vallez E, Lestavel S, Lefebvre P, Staels B. Hennuyer N, et al. Among authors: colin s. Atherosclerosis. 2016 Jun;249:200-8. doi: 10.1016/j.atherosclerosis.2016.03.003. Epub 2016 Mar 4. Atherosclerosis. 2016. PMID: 27108950
The neuron-derived orphan receptor 1 (NOR1) is induced upon human alternative macrophage polarization and stimulates the expression of markers of the M2 phenotype.
De Paoli F, Eeckhoute J, Copin C, Vanhoutte J, Duhem C, Derudas B, Dubois-Chevalier J, Colin S, Zawadzki C, Jude B, Haulon S, Lefebvre P, Staels B, Chinetti-Gbaguidi G. De Paoli F, et al. Among authors: colin s. Atherosclerosis. 2015 Jul;241(1):18-26. doi: 10.1016/j.atherosclerosis.2015.04.798. Epub 2015 Apr 26. Atherosclerosis. 2015. PMID: 25941992
140 results