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Stopping Tumor Necrosis Factor Inhibitor Treatment in Patients With Established Rheumatoid Arthritis in Remission or With Stable Low Disease Activity: A Pragmatic Multicenter, Open-Label Randomized Controlled Trial.
Ghiti Moghadam M, Vonkeman HE, Ten Klooster PM, Tekstra J, van Schaardenburg D, Starmans-Kool M, Brouwer E, Bos R, Lems WF, Colin EM, Allaart CF, Meek IL, Landewé R, Bernelot Moens HJ, van Riel PL, van de Laar MA, Jansen TL; Dutch National POET Collaboration. Ghiti Moghadam M, et al. Among authors: colin em. Arthritis Rheumatol. 2016 Aug;68(8):1810-7. doi: 10.1002/art.39626. Arthritis Rheumatol. 2016. PMID: 26866428 Clinical Trial.
Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production.
van Hamburg JP, Asmawidjaja PS, Davelaar N, Mus AM, Colin EM, Hazes JM, Dolhain RJ, Lubberts E. van Hamburg JP, et al. Among authors: colin em. Arthritis Rheum. 2011 Jan;63(1):73-83. doi: 10.1002/art.30093. Arthritis Rheum. 2011. PMID: 20954258 Free article.
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