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Factor inhibiting HIF can catalyze two asparaginyl hydroxylations in VNVN motifs of ankyrin fold proteins.
Leissing TM, Hardy AP, Chan H, Wang Y, Tumber A, Chowdhury R, Feng T, Coleman ML, Cockman ME, Kramer HB, Berridge G, Fischer R, Kessler BM, Ratcliffe PJ, Lu X, Schofield CJ. Leissing TM, et al. Among authors: coleman ml. J Biol Chem. 2022 Jun;298(6):102020. doi: 10.1016/j.jbc.2022.102020. Epub 2022 May 7. J Biol Chem. 2022. PMID: 35537551 Free PMC article.
Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH).
Cockman ME, Lancaster DE, Stolze IP, Hewitson KS, McDonough MA, Coleman ML, Coles CH, Yu X, Hay RT, Ley SC, Pugh CW, Oldham NJ, Masson N, Schofield CJ, Ratcliffe PJ. Cockman ME, et al. Among authors: coleman ml. Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14767-72. doi: 10.1073/pnas.0606877103. Epub 2006 Sep 26. Proc Natl Acad Sci U S A. 2006. PMID: 17003112 Free PMC article.
Angiogenesis: escape from hypoxia.
Coleman ML, Ratcliffe PJ. Coleman ML, et al. Nat Med. 2009 May;15(5):491-3. doi: 10.1038/nm0509-491. Nat Med. 2009. PMID: 19424207 No abstract available.
110 results