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Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1.
Coleman DJL, Keane P, Chin PS, Ames L, Kellaway S, Blair H, Khan N, Griffin J, Holmes E, Maytum A, Potluri S, Strate L, Koscielniak K, Raghavan M, Bushweller J, Heidenreich O, Rabbitts T, Cockerill PN, Bonifer C. Coleman DJL, et al. iScience. 2024 Mar 26;27(4):109576. doi: 10.1016/j.isci.2024.109576. eCollection 2024 Apr 19. iScience. 2024. PMID: 38638836 Free PMC article.
Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth.
Kellaway SG, Potluri S, Keane P, Blair HJ, Ames L, Worker A, Chin PS, Ptasinska A, Derevyanko PK, Adamo A, Coleman DJL, Khan N, Assi SA, Krippner-Heidenreich A, Raghavan M, Cockerill PN, Heidenreich O, Bonifer C. Kellaway SG, et al. Among authors: coleman djl. Nat Commun. 2024 Feb 14;15(1):1359. doi: 10.1038/s41467-024-45691-4. Nat Commun. 2024. PMID: 38355578 Free PMC article.
Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.
Coleman DJL, Keane P, Luque-Martin R, Chin PS, Blair H, Ames L, Kellaway SG, Griffin J, Holmes E, Potluri S, Assi SA, Bushweller J, Heidenreich O, Cockerill PN, Bonifer C. Coleman DJL, et al. bioRxiv [Preprint]. 2023 Jul 19:2023.07.18.549495. doi: 10.1101/2023.07.18.549495. bioRxiv. 2023. PMID: 37503022 Free PMC article. Updated. Preprint.
Asxl1 deletion disrupts MYC and RNA polymerase II function in granulocyte progenitors.
Braun TP, Estabrook J, Schonrock Z, Curtiss BM, Darmusey L, Macaraeg J, Enright T, Coblentz C, Callahan R, Yashar W, Taherinasab A, Mohammed H, Coleman DJ, Druker BJ, Demir E, Lusardi TA, Maxson JE. Braun TP, et al. Among authors: coleman dj. Leukemia. 2023 Feb;37(2):478-487. doi: 10.1038/s41375-022-01792-x. Epub 2022 Dec 16. Leukemia. 2023. PMID: 36526735 Free PMC article.
GoPeaks: histone modification peak calling for CUT&Tag.
Yashar WM, Kong G, VanCampen J, Curtiss BM, Coleman DJ, Carbone L, Yardimci GG, Maxson JE, Braun TP. Yashar WM, et al. Among authors: coleman dj. Genome Biol. 2022 Jul 4;23(1):144. doi: 10.1186/s13059-022-02707-w. Genome Biol. 2022. PMID: 35788238 Free PMC article.
306 results