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A conformational rearrangement of the SARS-CoV-2 host protein sigma-1 is required for antiviral activity: insights from a combined in-silico/in-vitro approach.
Abatematteo FS, Delre P, Mercurio I, Rezelj VV, Siliqi D, Beaucourt S, Lattanzi G, Colabufo NA, Leopoldo M, Saviano M, Vignuzzi M, Mangiatordi GF, Abate C. Abatematteo FS, et al. Among authors: colabufo na. Sci Rep. 2023 Aug 7;13(1):12798. doi: 10.1038/s41598-023-39662-w. Sci Rep. 2023. PMID: 37550340 Free PMC article.
Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase.
Intranuovo F, Brunetti L, DelRe P, Mangiatordi GF, Stefanachi A, Laghezza A, Niso M, Leonetti F, Loiodice F, Ligresti A, Kostrzewa M, Brea J, Loza MI, Sotelo E, Saviano M, Colabufo NA, Riganti C, Abate C, Contino M. Intranuovo F, et al. Among authors: colabufo na. J Med Chem. 2023 Jan 12;66(1):235-250. doi: 10.1021/acs.jmedchem.2c01084. Epub 2022 Dec 21. J Med Chem. 2023. PMID: 36542836
N-adamantyl-anthranil amide derivatives: New selective ligands for the cannabinoid receptor subtype 2 (CB2R).
Graziano G, Delre P, Carofiglio F, Brea J, Ligresti A, Kostrzewa M, Riganti C, Gioè-Gallo C, Majellaro M, Nicolotti O, Colabufo NA, Abate C, Loza MI, Sotelo E, Mangiatordi GF, Contino M, Stefanachi A, Leonetti F. Graziano G, et al. Among authors: colabufo na. Eur J Med Chem. 2023 Feb 15;248:115109. doi: 10.1016/j.ejmech.2023.115109. Epub 2023 Jan 13. Eur J Med Chem. 2023. PMID: 36657299
Design and synthesis of fluorescent ligands for the detection of cannabinoid type 2 receptor (CB2R).
Spinelli F, Giampietro R, Stefanachi A, Riganti C, Kopecka J, Abatematteo FS, Leonetti F, Colabufo NA, Mangiatordi GF, Nicolotti O, Perrone MG, Brea J, Loza MI, Infantino V, Abate C, Contino M. Spinelli F, et al. Among authors: colabufo na. Eur J Med Chem. 2020 Feb 15;188:112037. doi: 10.1016/j.ejmech.2020.112037. Epub 2020 Jan 7. Eur J Med Chem. 2020. PMID: 31954990 Free article.
Why PB28 Could Be a Covid 2019 Game Changer?
Colabufo NA, Leopoldo M, Ferorelli S, Abate C, Contino M, Perrone MG, Niso M, Perrone R, Berardi F. Colabufo NA, et al. ACS Med Chem Lett. 2020 Aug 14;11(10):2048-2050. doi: 10.1021/acsmedchemlett.0c00271. eCollection 2020 Oct 8. ACS Med Chem Lett. 2020. PMID: 33052254 Free PMC article.
180 results