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A programmable encapsulation system improves delivery of therapeutic bacteria in mice.
Harimoto T, Hahn J, Chen YY, Im J, Zhang J, Hou N, Li F, Coker C, Gray K, Harr N, Chowdhury S, Pu K, Nimura C, Arpaia N, Leong KW, Danino T. Harimoto T, et al. Among authors: coker c. Nat Biotechnol. 2022 Aug;40(8):1259-1269. doi: 10.1038/s41587-022-01244-y. Epub 2022 Mar 17. Nat Biotechnol. 2022. PMID: 35301496 Free PMC article.
Enhancing the tropism of bacteria via genetically programmed biosensors.
Chien T, Harimoto T, Kepecs B, Gray K, Coker C, Hou N, Pu K, Azad T, Nolasco A, Pavlicova M, Danino T. Chien T, et al. Among authors: coker c. Nat Biomed Eng. 2022 Jan;6(1):94-104. doi: 10.1038/s41551-021-00772-3. Epub 2021 Jul 29. Nat Biomed Eng. 2022. PMID: 34326488 Free PMC article.
Probiotic-guided CAR-T cells for solid tumor targeting.
Vincent RL, Gurbatri CR, Li F, Vardoshvili A, Coker C, Im J, Ballister ER, Rouanne M, Savage T, de Los Santos-Alexis K, Redenti A, Brockmann L, Komaranchath M, Arpaia N, Danino T. Vincent RL, et al. Among authors: coker c. Science. 2023 Oct 13;382(6667):211-218. doi: 10.1126/science.add7034. Epub 2023 Oct 12. Science. 2023. PMID: 37824640
Engineering tumor-colonizing E. coli Nissle 1917 for detection and treatment of colorectal neoplasia.
Gurbatri CR, Radford GA, Vrbanac L, Im J, Thomas EM, Coker C, Taylor SR, Jang Y, Sivan A, Rhee K, Saleh AA, Chien T, Zandkarimi F, Lia I, Lannagan TRM, Wang T, Wright JA, Kobayashi H, Ng JQ, Lawrence M, Sammour T, Thomas M, Lewis M, Papanicolas L, Perry J, Fitzsimmons T, Kaazan P, Lim A, Stavropoulos AM, Gouskos DA, Marker J, Ostroff C, Rogers G, Arpaia N, Worthley DL, Woods SL, Danino T. Gurbatri CR, et al. Among authors: coker c. Nat Commun. 2024 Jan 20;15(1):646. doi: 10.1038/s41467-024-44776-4. Nat Commun. 2024. PMID: 38245513 Free PMC article. Clinical Trial.
Metastatic cancers promote cachexia through ZIP14 upregulation in skeletal muscle.
Wang G, Biswas AK, Ma W, Kandpal M, Coker C, Grandgenett PM, Hollingsworth MA, Jain R, Tanji K, Lόpez-Pintado S, Borczuk A, Hebert D, Jenkitkasemwong S, Hojyo S, Davuluri RV, Knutson MD, Fukada T, Acharyya S. Wang G, et al. Among authors: coker c. Nat Med. 2018 Jun;24(6):770-781. doi: 10.1038/s41591-018-0054-2. Epub 2018 Jun 6. Nat Med. 2018. PMID: 29875463 Free PMC article.
152 results