Coinçon M - Search Results

1

Identification of the binding site of Brucella VirB8 interaction inhibitors.

Smith MA, Coinçon M, Paschos A, Jolicoeur B, Lavallée P, Sygusch J, Baron C. Smith MA, et al. Among authors: coincon m. Chem Biol. 2012 Aug 24;19(8):1041-8. doi: 10.1016/j.chembiol.2012.07.007. Chem Biol. 2012. PMID: 22921071

2

Crystal structure of reaction intermediates in pyruvate class II aldolase: substrate cleavage, enolate stabilization, and substrate specificity.

Coincon M, Wang W, Sygusch J, Seah SY. Coincon M, et al. J Biol Chem. 2012 Oct 19;287(43):36208-21. doi: 10.1074/jbc.M112.400705. Epub 2012 Aug 20. J Biol Chem. 2012. PMID: 22908224 Free PMC article.

3

Active site remodeling during the catalytic cycle in metal-dependent fructose-1,6-bisphosphate aldolases.

Jacques B, Coinçon M, Sygusch J. Jacques B, et al. Among authors: coincon m. J Biol Chem. 2018 May 18;293(20):7737-7753. doi: 10.1074/jbc.RA117.001098. Epub 2018 Mar 28. J Biol Chem. 2018. PMID: 29593097 Free PMC article.

4

Rational design, synthesis, and evaluation of new selective inhibitors of microbial class II (zinc dependent) fructose bis-phosphate aldolases.

Daher R, Coinçon M, Fonvielle M, Gest PM, Guerin ME, Jackson M, Sygusch J, Therisod M. Daher R, et al. Among authors: coincon m. J Med Chem. 2010 Nov 11;53(21):7836-42. doi: 10.1021/jm1009814. J Med Chem. 2010. PMID: 20929256 Free PMC article.

5

Peptides designed to spatially depict the Epstein-Barr virus major virion glycoprotein gp350 neutralization epitope elicit antibodies that block virus-neutralizing antibody 72A1 interaction with the native gp350 molecule.

Tanner JE, Coinçon M, Leblond V, Hu J, Fang JM, Sygusch J, Alfieri C. Tanner JE, et al. Among authors: coincon m. J Virol. 2015 May;89(9):4932-41. doi: 10.1128/JVI.03269-14. Epub 2015 Feb 18. J Virol. 2015. PMID: 25694592 Free PMC article.

6

Synthesis and biochemical evaluation of selective inhibitors of class II fructose bisphosphate aldolases: towards new synthetic antibiotics.

Fonvielle M, Coinçon M, Daher R, Desbenoit N, Kosieradzka K, Barilone N, Gicquel B, Sygusch J, Jackson M, Therisod M. Fonvielle M, et al. Among authors: coincon m. Chemistry. 2008;14(28):8521-9. doi: 10.1002/chem.200800857. Chemistry. 2008. PMID: 18688832

7

Glycolytic and non-glycolytic functions of Mycobacterium tuberculosis fructose-1,6-bisphosphate aldolase, an essential enzyme produced by replicating and non-replicating bacilli.

de la Paz Santangelo M, Gest PM, Guerin ME, Coinçon M, Pham H, Ryan G, Puckett SE, Spencer JS, Gonzalez-Juarrero M, Daher R, Lenaerts AJ, Schnappinger D, Therisod M, Ehrt S, Sygusch J, Jackson M. de la Paz Santangelo M, et al. Among authors: coincon m. J Biol Chem. 2011 Nov 18;286(46):40219-31. doi: 10.1074/jbc.M111.259440. Epub 2011 Sep 23. J Biol Chem. 2011. PMID: 21949126 Free PMC article.

8

Hydroxynaphthaldehyde phosphate derivatives as potent covalent Schiff base inhibitors of fructose-1,6-bisphosphate aldolase.

Dax C, Coinçon M, Sygusch J, Blonski C. Dax C, et al. Among authors: coincon m. Biochemistry. 2005 Apr 12;44(14):5430-43. doi: 10.1021/bi0477992. Biochemistry. 2005. PMID: 15807536

9

Aldolase is essential for energy production and bridging adhesin-actin cytoskeletal interactions during parasite invasion of host cells.

Starnes GL, Coincon M, Sygusch J, Sibley LD. Starnes GL, et al. Among authors: coincon m. Cell Host Microbe. 2009 Apr 23;5(4):353-64. doi: 10.1016/j.chom.2009.03.005. Cell Host Microbe. 2009. PMID: 19380114 Free PMC article.

10

Selective irreversible inhibition of fructose 1,6-bisphosphate aldolase from Trypanosoma brucei.

Dax C, Duffieux F, Chabot N, Coincon M, Sygusch J, Michels PA, Blonski C. Dax C, et al. Among authors: coincon m. J Med Chem. 2006 Mar 9;49(5):1499-502. doi: 10.1021/jm050237b. J Med Chem. 2006. PMID: 16509566

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