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Acarbose presents in vitro and in vivo antileishmanial activity against Leishmania infantum and is a promising therapeutic candidate against visceral leishmaniasis.
Costa RR, Oliveira-da-Silva JA, Reis TAR, Tavares GSV, Mendonça DVC, Freitas CS, Lage DP, Martins VT, Antinarelli LMR, Machado AS, Bandeira RS, Ludolf F, Santos TTO, Brito RCF, Humbert MV, Menezes-Souza D, Duarte MC, Chávez-Fumagalli MA, Roatt BM, Coimbra ES, Coelho EAF. Costa RR, et al. Among authors: coimbra es. Med Microbiol Immunol. 2021 Jun;210(2-3):133-147. doi: 10.1007/s00430-021-00707-4. Epub 2021 Apr 18. Med Microbiol Immunol. 2021. PMID: 33870453 Free PMC article.
Preparation and antileishmanial activity of lipophilic N-alkyl diamines.
da Costa CF, Coimbra ES, Braga FG, dos Reis RC, da Silva AD, de Almeida MV. da Costa CF, et al. Among authors: coimbra es. Biomed Pharmacother. 2009 Jan;63(1):40-2. doi: 10.1016/j.biopha.2007.12.013. Epub 2008 Jan 18. Biomed Pharmacother. 2009. PMID: 18262385
4-Aminoquinoline Derivatives as Potential Antileishmanial Agents.
Antinarelli LM, Dias RM, Souza IO, Lima WP, Gameiro J, da Silva AD, Coimbra ES. Antinarelli LM, et al. Among authors: coimbra es. Chem Biol Drug Des. 2015 Oct;86(4):704-14. doi: 10.1111/cbdd.12540. Epub 2015 Mar 11. Chem Biol Drug Des. 2015. PMID: 25682728
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