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Page 1
The role of fMRI in drug development.
Carmichael O, Schwarz AJ, Chatham CH, Scott D, Turner JA, Upadhyay J, Coimbra A, Goodman JA, Baumgartner R, English BA, Apolzan JW, Shankapal P, Hawkins KR. Carmichael O, et al. Among authors: coimbra a. Drug Discov Today. 2018 Feb;23(2):333-348. doi: 10.1016/j.drudis.2017.11.012. Epub 2017 Nov 15. Drug Discov Today. 2018. PMID: 29154758 Free PMC article. Review.
A procedural framework for good imaging practice in pharmacological fMRI studies applied to drug development #1: processes and requirements.
Schwarz AJ, Becerra L, Upadhyay J, Anderson J, Baumgartner R, Coimbra A, Evelhoch J, Hargreaves R, Robertson B, Iyengar S, Tauscher J, Bleakman D, Borsook D. Schwarz AJ, et al. Among authors: coimbra a. Drug Discov Today. 2011 Jul;16(13-14):583-93. doi: 10.1016/j.drudis.2011.05.006. Epub 2011 May 24. Drug Discov Today. 2011. PMID: 21635967 Review.
Imaging drugs with and without clinical analgesic efficacy.
Upadhyay J, Anderson J, Schwarz AJ, Coimbra A, Baumgartner R, Pendse G, George E, Nutile L, Wallin D, Bishop J, Neni S, Maier G, Iyengar S, Evelhoch JL, Bleakman D, Hargreaves R, Becerra L, Borsook D. Upadhyay J, et al. Among authors: coimbra a. Neuropsychopharmacology. 2011 Dec;36(13):2659-73. doi: 10.1038/npp.2011.156. Epub 2011 Aug 17. Neuropsychopharmacology. 2011. PMID: 21849979 Free PMC article. Clinical Trial.
Modulation of CNS pain circuitry by intravenous and sublingual doses of buprenorphine.
Upadhyay J, Anderson J, Baumgartner R, Coimbra A, Schwarz AJ, Pendse G, Wallin D, Nutile L, Bishop J, George E, Elman I, Sunkaraneni S, Maier G, Iyengar S, Evelhoch JL, Bleakman D, Hargreaves R, Becerra L, Borsook D. Upadhyay J, et al. Among authors: coimbra a. Neuroimage. 2012 Feb 15;59(4):3762-73. doi: 10.1016/j.neuroimage.2011.11.034. Epub 2011 Nov 18. Neuroimage. 2012. PMID: 22119647
Parallel buprenorphine phMRI responses in conscious rodents and healthy human subjects.
Becerra L, Upadhyay J, Chang PC, Bishop J, Anderson J, Baumgartner R, Schwarz AJ, Coimbra A, Wallin D, Nutile L, George E, Maier G, Sunkaraneni S, Iyengar S, Evelhoch JL, Bleakman D, Hargreaves R, Borsook D. Becerra L, et al. Among authors: coimbra a. J Pharmacol Exp Ther. 2013 Apr;345(1):41-51. doi: 10.1124/jpet.112.201145. Epub 2013 Jan 31. J Pharmacol Exp Ther. 2013. PMID: 23370795 Clinical Trial.
Evaluation of an fMRI USPIO-based assay in healthy human volunteers.
Baumgartner R, Cho W, Coimbra A, Chen C, Wang Z, Struyk A, Venketasubramanian N, Low M, Gargano C, Zhao F, Williams D, Reese T, Seah S, Feng D, Apreleva S, Petersen E, Evelhoch JL. Baumgartner R, et al. Among authors: coimbra a. J Magn Reson Imaging. 2017 Jul;46(1):124-133. doi: 10.1002/jmri.25499. Epub 2016 Oct 24. J Magn Reson Imaging. 2017. PMID: 27775841
267 results