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PAX6 regulates melanogenesis in the retinal pigmented epithelium through feed-forward regulatory interactions with MITF.
Raviv S, Bharti K, Rencus-Lazar S, Cohen-Tayar Y, Schyr R, Evantal N, Meshorer E, Zilberberg A, Idelson M, Reubinoff B, Grebe R, Rosin-Arbesfeld R, Lauderdale J, Lutty G, Arnheiter H, Ashery-Padan R. Raviv S, et al. Among authors: cohen tayar y. PLoS Genet. 2014 May 29;10(5):e1004360. doi: 10.1371/journal.pgen.1004360. eCollection 2014. PLoS Genet. 2014. PMID: 24875170 Free PMC article.
PAX6 maintains β cell identity by repressing genes of alternative islet cell types.
Swisa A, Avrahami D, Eden N, Zhang J, Feleke E, Dahan T, Cohen-Tayar Y, Stolovich-Rain M, Kaestner KH, Glaser B, Ashery-Padan R, Dor Y. Swisa A, et al. Among authors: cohen tayar y. J Clin Invest. 2017 Jan 3;127(1):230-243. doi: 10.1172/JCI88015. Epub 2016 Dec 12. J Clin Invest. 2017. PMID: 27941241 Free PMC article.
The LHX2-OTX2 transcriptional regulatory module controls retinal pigmented epithelium differentiation and underlies genetic risk for age-related macular degeneration.
Cohen-Gulkar M, David A, Messika-Gold N, Eshel M, Ovadia S, Zuk-Bar N, Idelson M, Cohen-Tayar Y, Reubinoff B, Ziv T, Shamay M, Elkon R, Ashery-Padan R. Cohen-Gulkar M, et al. Among authors: cohen tayar y. PLoS Biol. 2023 Jan 17;21(1):e3001924. doi: 10.1371/journal.pbio.3001924. eCollection 2023 Jan. PLoS Biol. 2023. PMID: 36649236 Free PMC article.