Cohen SB - Search Results

1

Functional interaction between compound heterozygous TERT mutations causes severe telomere biology disorder.

Niaz A, Truong J, Manoleras A, Fox LC, Blombery P, Vasireddy RS, Pickett HA, Curtin JA, Barbaro PM, Rodgers J, Roy J, Riley LG, Holien JK, Cohen SB, Bryan TM. Niaz A, et al. Among authors: cohen sb. Blood Adv. 2022 Jun 28;6(12):3779-3791. doi: 10.1182/bloodadvances.2022007029. Blood Adv. 2022. PMID: 35477117 Free PMC article.

2

Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions.

Cesare AJ, Kaul Z, Cohen SB, Napier CE, Pickett HA, Neumann AA, Reddel RR. Cesare AJ, et al. Among authors: cohen sb. Nat Struct Mol Biol. 2009 Dec;16(12):1244-51. doi: 10.1038/nsmb.1725. Epub 2009 Nov 22. Nat Struct Mol Biol. 2009. PMID: 19935685

3

Direct involvement of the TEN domain at the active site of human telomerase.

Jurczyluk J, Nouwens AS, Holien JK, Adams TE, Lovrecz GO, Parker MW, Cohen SB, Bryan TM. Jurczyluk J, et al. Among authors: cohen sb. Nucleic Acids Res. 2011 Mar;39(5):1774-88. doi: 10.1093/nar/gkq1083. Epub 2010 Nov 3. Nucleic Acids Res. 2011. PMID: 21051362 Free PMC article.

4

Telomerase recruitment requires both TCAB1 and Cajal bodies independently.

Stern JL, Zyner KG, Pickett HA, Cohen SB, Bryan TM. Stern JL, et al. Among authors: cohen sb. Mol Cell Biol. 2012 Jul;32(13):2384-95. doi: 10.1128/MCB.00379-12. Epub 2012 Apr 30. Mol Cell Biol. 2012. PMID: 22547674 Free PMC article.

5

Two-step mechanism involving active-site conformational changes regulates human telomerase DNA binding.

Tomlinson CG, Moye AL, Holien JK, Parker MW, Cohen SB, Bryan TM. Tomlinson CG, et al. Among authors: cohen sb. Biochem J. 2015 Jan 15;465(2):347-57. doi: 10.1042/BJ20140922. Biochem J. 2015. PMID: 25365545

6

Cancer. TERT promoter mutations and telomerase reactivation in urothelial cancer.

Borah S, Xi L, Zaug AJ, Powell NM, Dancik GM, Cohen SB, Costello JC, Theodorescu D, Cech TR. Borah S, et al. Among authors: cohen sb. Science. 2015 Feb 27;347(6225):1006-10. doi: 10.1126/science.1260200. Epub 2015 Feb 5. Science. 2015. PMID: 25722414 Free PMC article.

7

Telomeric G-quadruplexes are a substrate and site of localization for human telomerase.

Moye AL, Porter KC, Cohen SB, Phan T, Zyner KG, Sasaki N, Lovrecz GO, Beck JL, Bryan TM. Moye AL, et al. Among authors: cohen sb. Nat Commun. 2015 Jul 9;6:7643. doi: 10.1038/ncomms8643. Nat Commun. 2015. PMID: 26158869 Free PMC article.

8

Quantitative assays for measuring human telomerase activity and DNA binding properties.

Tomlinson CG, Sasaki N, Jurczyluk J, Bryan TM, Cohen SB. Tomlinson CG, et al. Among authors: cohen sb. Methods. 2017 Feb 1;114:85-95. doi: 10.1016/j.ymeth.2016.08.002. Epub 2016 Aug 6. Methods. 2017. PMID: 27507660

9

Human RTEL1 stabilizes long G-overhangs allowing telomerase-dependent over-extension.

Porreca RM, Glousker G, Awad A, Matilla Fernandez MI, Gibaud A, Naucke C, Cohen SB, Bryan TM, Tzfati Y, Draskovic I, Londoño-Vallejo A. Porreca RM, et al. Among authors: cohen sb. Nucleic Acids Res. 2018 May 18;46(9):4533-4545. doi: 10.1093/nar/gky173. Nucleic Acids Res. 2018. PMID: 29522136 Free PMC article.

10

A mechanism for the extension and unfolding of parallel telomeric G-quadruplexes by human telomerase at single-molecule resolution.

Paudel BP, Moye AL, Abou Assi H, El-Khoury R, Cohen SB, Holien JK, Birrento ML, Samosorn S, Intharapichai K, Tomlinson CG, Teulade-Fichou MP, González C, Beck JL, Damha MJ, van Oijen AM, Bryan TM. Paudel BP, et al. Among authors: cohen sb. Elife. 2020 Jul 29;9:e56428. doi: 10.7554/eLife.56428. Elife. 2020. PMID: 32723475 Free PMC article.

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