Coen DM - Search Results

1

A small molecule exerts selective antiviral activity by targeting the human cytomegalovirus nuclear egress complex.

Chen H, Lye MF, Gorgulla C, Ficarro SB, Cuny GD, Scott DA, Wu F, Rothlauf PW, Wang X, Fernandez R, Pesola JM, Draga S, Marto JA, Hogle JM, Arthanari H, Coen DM. Chen H, et al. Among authors: coen dm. PLoS Pathog. 2023 Nov 17;19(11):e1011781. doi: 10.1371/journal.ppat.1011781. eCollection 2023 Nov. PLoS Pathog. 2023. PMID: 37976321 Free PMC article.

2

The enzymological basis for resistance of herpesvirus DNA polymerase mutants to acyclovir: relationship to the structure of alpha-like DNA polymerases.

Huang L, Ishii KK, Zuccola H, Gehring AM, Hwang CB, Hogle J, Coen DM. Huang L, et al. Among authors: coen dm. Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):447-52. doi: 10.1073/pnas.96.2.447. Proc Natl Acad Sci U S A. 1999. PMID: 9892653 Free PMC article.

3

The crystal structure of an unusual processivity factor, herpes simplex virus UL42, bound to the C terminus of its cognate polymerase.

Zuccola HJ, Filman DJ, Coen DM, Hogle JM. Zuccola HJ, et al. Among authors: coen dm. Mol Cell. 2000 Feb;5(2):267-78. doi: 10.1016/s1097-2765(00)80422-0. Mol Cell. 2000. PMID: 10882068 Free article.

4

Residues of human cytomegalovirus DNA polymerase catalytic subunit UL54 that are necessary and sufficient for interaction with the accessory protein UL44.

Loregian A, Appleton BA, Hogle JM, Coen DM. Loregian A, et al. Among authors: coen dm. J Virol. 2004 Jan;78(1):158-67. doi: 10.1128/jvi.78.1.158-167.2004. J Virol. 2004. PMID: 14671097 Free PMC article.

5

The cytomegalovirus DNA polymerase subunit UL44 forms a C clamp-shaped dimer.

Appleton BA, Loregian A, Filman DJ, Coen DM, Hogle JM. Appleton BA, et al. Among authors: coen dm. Mol Cell. 2004 Jul 23;15(2):233-44. doi: 10.1016/j.molcel.2004.06.018. Mol Cell. 2004. PMID: 15260974 Free article.

6

Specific residues in the connector loop of the human cytomegalovirus DNA polymerase accessory protein UL44 are crucial for interaction with the UL54 catalytic subunit.

Loregian A, Appleton BA, Hogle JM, Coen DM. Loregian A, et al. Among authors: coen dm. J Virol. 2004 Sep;78(17):9084-92. doi: 10.1128/JVI.78.17.9084-9092.2004. J Virol. 2004. PMID: 15308704 Free PMC article.

7

Binding of herpes simplex virus-1 US11 to specific RNA sequences.

Bryant KF, Cox JC, Wang H, Hogle JM, Ellington AD, Coen DM. Bryant KF, et al. Among authors: coen dm. Nucleic Acids Res. 2005 Oct 24;33(19):6090-100. doi: 10.1093/nar/gki919. Print 2005. Nucleic Acids Res. 2005. PMID: 16246910 Free PMC article.

8

Herpes simplex virus 1 immediate-early and early gene expression during reactivation from latency under conditions that prevent infectious virus production.

Pesola JM, Zhu J, Knipe DM, Coen DM. Pesola JM, et al. Among authors: coen dm. J Virol. 2005 Dec;79(23):14516-25. doi: 10.1128/JVI.79.23.14516-14525.2005. J Virol. 2005. PMID: 16282451 Free PMC article.

9

Crystal structure of the cytomegalovirus DNA polymerase subunit UL44 in complex with the C terminus from the catalytic subunit. Differences in structure and function relative to unliganded UL44.

Appleton BA, Brooks J, Loregian A, Filman DJ, Coen DM, Hogle JM. Appleton BA, et al. Among authors: coen dm. J Biol Chem. 2006 Feb 24;281(8):5224-32. doi: 10.1074/jbc.M506900200. Epub 2005 Dec 20. J Biol Chem. 2006. PMID: 16371349 Free article.

10

In vivo fitness and virulence of a drug-resistant herpes simplex virus 1 mutant.

Pesola JM, Coen DM. Pesola JM, et al. Among authors: coen dm. J Gen Virol. 2007 May;88(Pt 5):1410-1414. doi: 10.1099/vir.0.82787-0. J Gen Virol. 2007. PMID: 17412967

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