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A novel process driving Alzheimer's disease validated in a mouse model: Therapeutic potential.
Greenfield SA, Cole GM, Coen CW, Frautschy S, Singh RP, Mekkittikul M, Garcia-Ratés S, Morrill P, Hollings O, Passmore M, Hasan S, Carty N, Bison S, Piccoli L, Carletti R, Tacconi S, Chalidou A, Pedercini M, Kroecher T, Astner H, Gerrard PA. Greenfield SA, et al. Among authors: coen cw. Alzheimers Dement (N Y). 2022 Apr 5;8(1):e12274. doi: 10.1002/trc2.12274. eCollection 2022. Alzheimers Dement (N Y). 2022. PMID: 35415206 Free PMC article.
(I) Pharmacological profiling of a novel modulator of the α7 nicotinic receptor: Blockade of a toxic acetylcholinesterase-derived peptide increased in Alzheimer brains.
Garcia-Ratés S, Morrill P, Tu H, Pottiez G, Badin AS, Tormo-Garcia C, Heffner C, Coen CW, Greenfield SA. Garcia-Ratés S, et al. Among authors: coen cw. Neuropharmacology. 2016 Jun;105:487-499. doi: 10.1016/j.neuropharm.2016.02.006. Epub 2016 Feb 8. Neuropharmacology. 2016. PMID: 26867503
The isoflavone Equol mediates rapid vascular relaxation: Ca2+-independent activation of endothelial nitric-oxide synthase/Hsp90 involving ERK1/2 and Akt phosphorylation in human endothelial cells.
Joy S, Siow RC, Rowlands DJ, Becker M, Wyatt AW, Aaronson PI, Coen CW, Kallo I, Jacob R, Mann GE. Joy S, et al. Among authors: coen cw. J Biol Chem. 2006 Sep 15;281(37):27335-45. doi: 10.1074/jbc.M602803200. Epub 2006 Jul 13. J Biol Chem. 2006. PMID: 16840783 Free article.
94 results