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Clotrimazole is effective for the regression of endometriotic implants in a Wistar rat experimental model of endometriosis.
Machado DE, Perini JA, de Mendonça EM, Branco JR, Rodrigues-Baptista KC, Alessandra-Perini J, Espíndola-Netto JM, Dos Santos TA, Coelho WS, Nasciutti LE, Sola-Penna M, Zancan P. Machado DE, et al. Among authors: coelho ws. Mol Cell Endocrinol. 2018 Nov 15;476:17-26. doi: 10.1016/j.mce.2018.04.005. Epub 2018 Apr 22. Mol Cell Endocrinol. 2018. PMID: 29689297 Free article.
Serotonin activates glycolysis and mitochondria biogenesis in human breast cancer cells through activation of the Jak1/STAT3/ERK1/2 and adenylate cyclase/PKA, respectively.
Sola-Penna M, Paixão LP, Branco JR, Ochioni AC, Albanese JM, Mundim DM, Baptista-de-Souza D, Figueiredo CP, Coelho WS, Marcondes MC, Zancan P. Sola-Penna M, et al. Among authors: coelho ws. Br J Cancer. 2020 Jan;122(2):194-208. doi: 10.1038/s41416-019-0640-1. Epub 2019 Dec 10. Br J Cancer. 2020. PMID: 31819176 Free PMC article.
Clotrimazole is effective, safe and tolerable for the treatment of endometriosis and functions by downregulating inducible nitric oxide synthase and modulating oxidative stress biomarkers.
Machado DE, Saggioro EM, Sales Junior SF, Alessandra-Perini J, de Campos Gomes Diniz L, Coelho WS, Zancan P, Perini JA. Machado DE, et al. Among authors: coelho ws. Mol Cell Endocrinol. 2023 Mar 15;564:111883. doi: 10.1016/j.mce.2023.111883. Epub 2023 Feb 2. Mol Cell Endocrinol. 2023. PMID: 36736881
15 results