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Page 1
Stem cell-derived systems in toxicology assessment.
Suter-Dick L, Alves PM, Blaauboer BJ, Bremm KD, Brito C, Coecke S, Flick B, Fowler P, Hescheler J, Ingelman-Sundberg M, Jennings P, Kelm JM, Manou I, Mistry P, Moretto A, Roth A, Stedman D, van de Water B, Beilmann M. Suter-Dick L, et al. Among authors: coecke s. Stem Cells Dev. 2015 Jun 1;24(11):1284-96. doi: 10.1089/scd.2014.0540. Epub 2015 Mar 31. Stem Cells Dev. 2015. PMID: 25675366 Review.
Blood-brain barrier in vitro models and their application in toxicology. The report and recommendations of ECVAM Workshop 49.
Prieto P, Blaauboer BJ, de Boer AG, Boveri M, Cecchelli R, Clemedson C, Coecke S, Forsby A, Galla HJ, Garberg P, Greenwood J, Price A, Tähti H; European Centre for the Validation of Alternative Methods. Prieto P, et al. Among authors: coecke s. Altern Lab Anim. 2004 Mar;32(1):37-50. doi: 10.1177/026119290403200107. Altern Lab Anim. 2004. PMID: 15603552 Review. No abstract available.
Toxicokinetics and metabolism.
Coecke S, Blaauboer BJ, Elaut G, Freeman S, Freidig A, Gensmantel N, Hoet P, Kapoulas VM, Ladstetter B, Langley G, Leahy D, Mannens G, Meneguz A, Monshouwer M, Nemery B, Pelkonen O, Pfaller W, Prieto P, Proctor N, Rogiers V, Rostami-Hodjegan A, Sabbioni E, Steiling W, van de Sandt JJ. Coecke S, et al. Altern Lab Anim. 2005 Jul;33 Suppl 1:147-75. doi: 10.1177/026119290503301s15. Altern Lab Anim. 2005. PMID: 16194147 No abstract available.
Metabolism: a bottleneck in in vitro toxicological test development. The report and recommendations of ECVAM workshop 54.
Coecke S, Ahr H, Blaauboer BJ, Bremer S, Casati S, Castell J, Combes R, Corvi R, Crespi CL, Cunningham ML, Elaut G, Eletti B, Freidig A, Gennari A, Ghersi-Egea JF, Guillouzo A, Hartung T, Hoet P, Ingelman-Sundberg M, Munn S, Janssens W, Ladstetter B, Leahy D, Long A, Meneguz A, Monshouwer M, Morath S, Nagelkerke F, Pelkonen O, Ponti J, Prieto P, Richert L, Sabbioni E, Schaack B, Steiling W, Testai E, Vericat JA, Worth A. Coecke S, et al. Altern Lab Anim. 2006 Feb;34(1):49-84. doi: 10.1177/026119290603400113. Altern Lab Anim. 2006. PMID: 16522150 No abstract available.
Physiologically-based Kinetic Modelling (PBK Modelling): meeting the 3Rs agenda. The report and recommendations of ECVAM Workshop 63.
Bouvier d'Yvoire M, Prieto P, Blaauboer BJ, Bois FY, Boobis A, Brochot C, Coecke S, Freidig A, Gundert-Remy U, Hartung T, Jacobs MN, Lavé T, Leahy DE, Lennernäs H, Loizou GD, Meek B, Pease C, Rowland M, Spendiff M, Yang J, Zeilmaker M. Bouvier d'Yvoire M, et al. Among authors: coecke s. Altern Lab Anim. 2007 Dec;35(6):661-71. doi: 10.1177/026119290703500606. Altern Lab Anim. 2007. PMID: 18186671 No abstract available.
Stem-cell culture on patterned bio-functional surfaces.
Ruiz A, Buzanska L, Ceriotti L, Bretagnol F, Coecke S, Colpo P, Rossi F. Ruiz A, et al. Among authors: coecke s. J Biomater Sci Polym Ed. 2008;19(12):1649-57. doi: 10.1163/156856208786440514. J Biomater Sci Polym Ed. 2008. PMID: 19017477
Report from the EPAA workshop: in vitro ADME in safety testing used by EPAA industry sectors.
Schroeder K, Bremm KD, Alépée N, Bessems JG, Blaauboer B, Boehn SN, Burek C, Coecke S, Gombau L, Hewitt NJ, Heylings J, Huwyler J, Jaeger M, Jagelavicius M, Jarrett N, Ketelslegers H, Kocina I, Koester J, Kreysa J, Note R, Poth A, Radtke M, Rogiers V, Scheel J, Schulz T, Steinkellner H, Toeroek M, Whelan M, Winkler P, Diembeck W. Schroeder K, et al. Among authors: coecke s. Toxicol In Vitro. 2011 Apr;25(3):589-604. doi: 10.1016/j.tiv.2010.12.005. Epub 2010 Dec 15. Toxicol In Vitro. 2011. PMID: 21167275 Free article. Review.
Toward preclinical predictive drug testing for metabolism and hepatotoxicity by using in vitro models derived from human embryonic stem cells and human cell lines - a report on the Vitrocellomics EU-project.
Mandenius CF, Andersson TB, Alves PM, Batzl-Hartmann C, Björquist P, Carrondo MJ, Chesne C, Coecke S, Edsbagge J, Fredriksson JM, Gerlach JC, Heinzle E, Ingelman-Sundberg M, Johansson I, Küppers-Munther B, Müller-Vieira U, Noor F, Zeilinger K. Mandenius CF, et al. Among authors: coecke s. Altern Lab Anim. 2011 May;39(2):147-71. doi: 10.1177/026119291103900210. Altern Lab Anim. 2011. PMID: 21639679
Three-dimensional HepaRG model as an attractive tool for toxicity testing.
Leite SB, Wilk-Zasadna I, Zaldivar JM, Airola E, Reis-Fernandes MA, Mennecozzi M, Guguen-Guillouzo C, Chesne C, Guillou C, Alves PM, Coecke S. Leite SB, et al. Among authors: coecke s. Toxicol Sci. 2012 Nov;130(1):106-16. doi: 10.1093/toxsci/kfs232. Epub 2012 Jul 27. Toxicol Sci. 2012. PMID: 22843569
128 results