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A carrier protein strategy yields the structure of dalbavancin.
Economou NJ, Nahoum V, Weeks SD, Grasty KC, Zentner IJ, Townsend TM, Bhuiya MW, Cocklin S, Loll PJ. Economou NJ, et al. Among authors: cocklin s. J Am Chem Soc. 2012 Mar 14;134(10):4637-45. doi: 10.1021/ja208755j. Epub 2012 Mar 1. J Am Chem Soc. 2012. PMID: 22352468 Free PMC article.
PDZ domains facilitate binding of high temperature requirement protease A (HtrA) and tail-specific protease (Tsp) to heterologous substrates through recognition of the small stable RNA A (ssrA)-encoded peptide.
Spiers A, Lamb HK, Cocklin S, Wheeler KA, Budworth J, Dodds AL, Pallen MJ, Maskell DJ, Charles IG, Hawkins AR. Spiers A, et al. Among authors: cocklin s. J Biol Chem. 2002 Oct 18;277(42):39443-9. doi: 10.1074/jbc.M202790200. Epub 2002 Aug 12. J Biol Chem. 2002. PMID: 12177052 Free article.
Structural determinants for affinity enhancement of a dual antagonist peptide entry inhibitor of human immunodeficiency virus type-1.
Gopi H, Umashankara M, Pirrone V, LaLonde J, Madani N, Tuzer F, Baxter S, Zentner I, Cocklin S, Jawanda N, Miller SR, Schön A, Klein JC, Freire E, Krebs FC, Smith AB, Sodroski J, Chaiken I. Gopi H, et al. Among authors: cocklin s. J Med Chem. 2008 May 8;51(9):2638-47. doi: 10.1021/jm070814r. Epub 2008 Apr 11. J Med Chem. 2008. PMID: 18402432 Free PMC article.
Conformational and structural features of HIV-1 gp120 underlying the dual receptor antagonism by cross-reactive neutralizing antibody m18.
Gift SK, Zentner IJ, Schön A, McFadden K, Umashankara M, Rajagopal S, Contarino M, Duffy C, Courter JR, Zhang MY, Gershoni JM, Cocklin S, Dimitrov DS, Smith AB 3rd, Freire E, Chaiken IM. Gift SK, et al. Among authors: cocklin s. Biochemistry. 2011 Apr 12;50(14):2756-68. doi: 10.1021/bi101160r. Epub 2011 Mar 18. Biochemistry. 2011. PMID: 21351734 Free PMC article.
82 results