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Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands.
Dichiara M, Ambrosio FA, Barbaraci C, González-Cano R, Costa G, Parenti C, Marrazzo A, Pasquinucci L, Cobos EJ, Alcaro S, Amata E. Dichiara M, et al. Among authors: cobos ej. ACS Chem Neurosci. 2023 May 17;14(10):1845-1858. doi: 10.1021/acschemneuro.3c00074. Epub 2023 May 8. ACS Chem Neurosci. 2023. PMID: 37155827 Free PMC article.
Adults with excess weight or obesity, but not with overweight, report greater pain intensities than individuals with normal weight: a systematic review and meta-analysis.
Garcia MM, Corrales P, Huerta MÁ, Czachorowski MJ, López-Miranda V, Medina-Gómez G, Cobos EJ, Goicoechea C, Molina-Álvarez M. Garcia MM, et al. Among authors: cobos ej. Front Endocrinol (Lausanne). 2024 Mar 6;15:1340465. doi: 10.3389/fendo.2024.1340465. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38510698 Free PMC article.
Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity.
Dichiara M, Ambrosio FA, Lee SM, Ruiz-Cantero MC, Lombino J, Coricello A, Costa G, Shah D, Costanzo G, Pasquinucci L, Son KN, Cosentino G, González-Cano R, Marrazzo A, Aakalu VK, Cobos EJ, Alcaro S, Amata E. Dichiara M, et al. Among authors: cobos ej. J Med Chem. 2023 Aug 24;66(16):11447-11463. doi: 10.1021/acs.jmedchem.3c00959. Epub 2023 Aug 3. J Med Chem. 2023. PMID: 37535861 Free PMC article.
Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain.
Szczepańska K, Karcz T, Dichiara M, Mogilski S, Kalinowska-Tłuścik J, Pilarski B, Leniak A, Pietruś W, Podlewska S, Popiołek-Barczyk K, Humphrys LJ, Ruiz-Cantero MC, Reiner-Link D, Leitzbach L, Łażewska D, Pockes S, Górka M, Zmysłowski A, Calmels T, Cobos EJ, Marrazzo A, Stark H, Bojarski AJ, Amata E, Kieć-Kononowicz K. Szczepańska K, et al. Among authors: cobos ej. J Med Chem. 2023 Jul 27;66(14):9658-9683. doi: 10.1021/acs.jmedchem.3c00430. Epub 2023 Jul 7. J Med Chem. 2023. PMID: 37418295 Free PMC article.
Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors.
Codony S, Entrena JM, Calvó-Tusell C, Jora B, González-Cano R, Osuna S, Corpas R, Morisseau C, Pérez B, Barniol-Xicota M, Griñán-Ferré C, Pérez C, Rodríguez-Franco MI, Martínez AL, Loza MI, Pallàs M, Verhelst SHL, Sanfeliu C, Feixas F, Hammock BD, Brea J, Cobos EJ, Vázquez S. Codony S, et al. Among authors: cobos ej. J Med Chem. 2022 Oct 27;65(20):13660-13680. doi: 10.1021/acs.jmedchem.2c00515. Epub 2022 Oct 12. J Med Chem. 2022. PMID: 36222708 Free PMC article.
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