Cobbaut M - Search Results

1

Dysfunctional Mechanotransduction through the YAP/TAZ/Hippo Pathway as a Feature of Chronic Disease.

Cobbaut M, Karagil S, Bruno L, Diaz de la Loza MDC, Mackenzie FE, Stolinski M, Elbediwy A. Cobbaut M, et al. Cells. 2020 Jan 8;9(1):151. doi: 10.3390/cells9010151. Cells. 2020. PMID: 31936297 Free PMC article. Review.

2

The Rho family GEF FARP2 is activated by aPKCι to control tight junction formation and polarity.

Elbediwy A, Zhang Y, Cobbaut M, Riou P, Tan RS, Roberts SK, Tynan C, George R, Kjaer S, Martin-Fernandez ML, Thompson BJ, McDonald NQ, Parker PJ. Elbediwy A, et al. Among authors: cobbaut m. J Cell Sci. 2019 Apr 25;132(8):jcs223743. doi: 10.1242/jcs.223743. J Cell Sci. 2019. PMID: 30872454 Free PMC article.

3

Genome-Protective Topoisomerase 2a-Dependent G2 Arrest Requires p53 in hTERT-Positive Cancer Cells.

Lockwood N, Martini S, Lopez-Pardo A, Deiss K, Segeren HA, Semple RK, Collins I, Repana D, Cobbaut M, Soliman T, Ciccarelli F, Parker PJ. Lockwood N, et al. Among authors: cobbaut m. Cancer Res. 2022 May 3;82(9):1762-1773. doi: 10.1158/0008-5472.CAN-21-1785. Cancer Res. 2022. PMID: 35247890 Free PMC article.

4

Protein kinase D displays intrinsic Tyr autophosphorylation activity: insights into mechanism and regulation.

Cobbaut M, Derua R, Parker PJ, Waelkens E, Janssens V, Van Lint J. Cobbaut M, et al. FEBS Lett. 2018 Jul;592(14):2432-2443. doi: 10.1002/1873-3468.13171. Epub 2018 Jul 23. FEBS Lett. 2018. PMID: 29933512 Free PMC article.

5

Equivocal, explicit and emergent actions of PKC isoforms in cancer.

Parker PJ, Brown SJ, Calleja V, Chakravarty P, Cobbaut M, Linch M, Marshall JJT, Martini S, McDonald NQ, Soliman T, Watson L. Parker PJ, et al. Among authors: cobbaut m. Nat Rev Cancer. 2021 Jan;21(1):51-63. doi: 10.1038/s41568-020-00310-4. Epub 2020 Nov 11. Nat Rev Cancer. 2021. PMID: 33177705 Review.

6

Protein kinase D2: a versatile player in cancer biology.

Azoitei N, Cobbaut M, Becher A, Van Lint J, Seufferlein T. Azoitei N, et al. Among authors: cobbaut m. Oncogene. 2018 Mar;37(10):1263-1278. doi: 10.1038/s41388-017-0052-8. Epub 2017 Dec 20. Oncogene. 2018. PMID: 29259300 Review.

7

Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop.

Cobbaut M, Derua R, Döppler H, Lou HJ, Vandoninck S, Storz P, Turk BE, Seufferlein T, Waelkens E, Janssens V, Van Lint J. Cobbaut M, et al. Sci Rep. 2017 Apr 20;7(1):887. doi: 10.1038/s41598-017-00800-w. Sci Rep. 2017. PMID: 28428613 Free PMC article.

8

Function and Regulation of Protein Kinase D in Oxidative Stress: A Tale of Isoforms.

Cobbaut M, Van Lint J. Cobbaut M, et al. Oxid Med Cell Longev. 2018 Apr 26;2018:2138502. doi: 10.1155/2018/2138502. eCollection 2018. Oxid Med Cell Longev. 2018. PMID: 29854077 Free PMC article. Review.

9

Discovery of a potent protein kinase D inhibitor: insights in the binding mode of pyrazolo[3,4-d]pyrimidine analogues.

Verschueren K, Cobbaut M, Demaerel J, Saadah L, Voet ARD, Van Lint J, De Borggraeve WM. Verschueren K, et al. Among authors: cobbaut m. Medchemcomm. 2017 Mar 1;8(3):640-646. doi: 10.1039/c6md00675b. Epub 2017 Feb 9. Medchemcomm. 2017. PMID: 28890776 Free PMC article.

10

Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyrimidine-based protein kinase D inhibitors.

Gilles P, Kashyap RS, Freitas MJ, Ceusters S, Van Asch K, Janssens A, De Jonghe S, Persoons L, Cobbaut M, Daelemans D, Van Lint J, Voet ARD, De Borggraeve WM. Gilles P, et al. Among authors: cobbaut m. Eur J Med Chem. 2020 Nov 1;205:112638. doi: 10.1016/j.ejmech.2020.112638. Epub 2020 Jul 29. Eur J Med Chem. 2020. PMID: 32835918

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